Protein Alignment ppk12 and mec-10

DIOPT Version :9

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_509438.1
• Gene: mec-10 / 181101
• WormBaseID: WBGene00003174
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 116/661 - (17%)
• Similarity: 206/661 - (31%)
• Gaps: 209/661 - (31%)

  Fly    26 LRQFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALII-----------------TVHLISNIY 73
            |:||..:||.||:..:|.:     ..|.:..::|..|:|                 .:..|::|.
 Worm    97 LQQFCYKTSSHGIPMLGQA-----PNSLYRAAWVFLLLICAIQFINQAVAVIQKYQKMDKITDIQ 156

  Fly    74 VKWDSTPVIIGISPQATSILKVPFPAITICNMNQVQRSLVANY---------------------- 116
            :|:|:                .||||||:||:|..:.|::.::
 Worm   157 LKFDT----------------APFPAITLCNLNPYKDSVIRSHDSISKILGVFKSVMKKAGDSSS 205

  Fly   117 --------------------------------------------REGSNESALLKLLCE------ 131
                                                        .:||||       ||
 Worm   206 EALEEEEETEYDMNGITIQAKRKKRGAGEKGTFEPANSACECDEEDGSNE-------CEERSTEK 263

  Fly   132 ----------------SDSW-----------ESSEADEEFSASNFVTNNLKISEFVSNHSQSCER 169
                            :|:|           .....||.:..|.......|.|| :......||.
 Worm   264 PSGDNDMCICAFDRQTNDAWPCHRKEQWTNTTCQTCDEHYLCSKKAKKGTKRSE-LKKEPCICES 327

  Fly   170 MLLFC---RFSAVERNC------SQLFQQILTDEGLCCVFNFQPPEYLYKPFANNN--------- 216
            ..|||   ..:|:..|.      |:.|.:|.|:|.....|.....|......|..|
 Worm   328 KGLFCIKHEHAAMVLNLWEYFGDSEDFSEISTEEREALGFGNMTDEVAIVTKAKENIIFAMSALS 392

  Fly   217 -----------RNLTNSDGFESVMWDPESGYPEQLPPKFYPA-----------TASGTGITLGFT 259
                       .||.:...|.....|.:..:.....|.|...           ::...|...|..
 Worm   393 EEQRILMSQAKHNLIHKCSFNGKPCDIDQDFELVADPTFGNCFVFNHDREIFKSSVRAGPQYGLR 457

  Fly   260 AVLDAEMGEYYCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSIS 324
            .:|.....:|..:| ...|.::..|:..:.|.....|..:..||.:::.:.|.:...:||...
 Worm   458 VMLFVNASDYLPTS-EAVGIRLTIHDKDDFPFPDTFGYSAPTGYISSFGMRMKKMSRLPAPYG-- 519

  Fly   325 RDGRQCLFKNEKELIFYR--IYTRLNCENECLAAFLYDTCSCIPFDHPLI--YSNASICSMGDTS 385
                .|:.........|:  .|:...|...|....:.|.|.|.....|.|  .....:.:.....
 Worm   520 ----DCVEDGATSNYIYKGYAYSTEGCYRTCFQELIIDRCGCSDPRFPSIGGVQPCQVFNKNHRE 580

  Fly   386 CV-RRAQRASNRPGWAKCR--QQCLPSCFDLNYLASGFSFPLASNNFQLANA--LVESFNKSYLS 445
            |: :...:.....|..|||  |.|..:.:..:|  |...:|..:.|..|...  ..|..|:.| .
 Worm   581 CLEKHTHQIGEIHGSFKCRCQQPCNQTIYTTSY--SEAIWPSQALNISLGQCEKEAEECNEEY-K 642

  Fly   446 KNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFV 510
            :|.|::.|::....:...:::...|:.:.:::.||.:||:.|.||::..|.:....     ||..
 Worm   643 ENAAMLEVFYEALNFEVLSESEAYGIVKMMADFGGHLGLWSGVSVMTCCEFVCLAF-----ELIY 702

  Fly   511 WKRSSHVDSEK 521
            ...:.|::.::
 Worm   703 MAIAHHINQQR 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	112/635 (18%)
		ASC	29..499	CDD:279230	111/634 (18%)
mec-10	NP_509438.1	ASC	88..723	CDD:295594	116/661 (18%)
		deg-1	99..696	CDD:273309	112/635 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162328
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7217
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.600