Protein Alignment ppk12 and unc-8

DIOPT Version :10

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001294293.1
• Gene: unc-8 / 177494
• WormBaseID: WBGene00006748
• Length: 778
• Species: Caenorhabditis elegans
• Alignment Length: 811
• Identity: 151/811 - (18%)
• Similarity: 245/811 - (30%)
• Gaps: 343/811 - (42%)

  Fly     1 MEPSPSAG---------------------TERQGSSLFLLKS--------FVRSL-RQFLNQTSL 35
            :.|||.||                     :||:.||...|:|        .::|| ..|..:||.
 Worm    50 IRPSPYAGGVHPHFEEEDDRSKLHASALYSERRTSSRKSLRSQKIDYHTTTIKSLWFDFCARTSS 114

  Fly    36 HGLKFVGDSGLSSWERSFFLGSFV-TALIITVHLISNIYVKWDSTPVIIGISPQATSILKV---- 95
            ||:.:|..|       ||| |.:| .||.:.:.:...:...|..:..:     |..:|:::
 Worm   115 HGIPYVATS-------SFF-GRYVWAALFMCMLMAFLLQTYWTMSEYL-----QYRTIIEMQLQF 166

  Fly    96 ---PFPAITICNMNQVQRSLVANYRE--------------------------------------- 118
               .|||.|:||:|..:.|.:..|.|
 Worm   167 EAAAFPAATVCNLNAFKYSELTQYEEIKEGFDYWERVINARMMSDSMKPGGDILEAISVRKKRSK 231

  Fly   119 ----------------------------------------------------------------- 118
                                                                             
 Worm   232 SRDQLLFPIDDEDLEGAVYQPVFVRCTCMNMEQCVPNRNPLEVNASICMCFEDVTRGLIWPCYPT 296

  Fly   119 ---------------------GSNES-------ALLKLLCESDS-------------W------- 135
                                 |.|.|       :.|..||:|.|             |
 Worm   297 SVWTVKKCSGCSISNTCPDPDGPNASKQIAKHNSPLPCLCQSISHHCMVHPKDEIRWWNPNNYTV 361

  Fly   136 ---------ESSEADEEFSASNF-----VTNNLKIS----------EFVSNHSQSCERMLLFCRF 176
                     |.:|.:|.|..|:.     :|...|.:          |...|.|.:....:|.|.|
 Worm   362 YSVTEPPTTEITETEEAFGLSDLKDAGAITTQTKENLIFLVAALPRETRRNLSYTLNEFVLRCSF 426

  Fly   177 SAVERNCSQLFQQILTDE-GLCCVFNFQPPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQL 240
            ::.:.:..:.|:..:..| |.|..|||           |::..|.|
 Worm   427 NSKDCSMERDFKLHVDPEYGNCYTFNF-----------NDSVELKN------------------- 461

  Fly   241 PPKFYPATASGTGITLGFTAVLDAEMGEYYCSSTNGPGFKVYFHNPIEVP------KVKEAGLIS 299
                     |..|...|...:|:....: |..:|...|.::..|...:.|      .....|.||
 Worm   462 ---------SRAGPMYGLRLLLNVHQSD-YMPTTEAAGVRLVVHEQDQEPFPDTFGYSAPTGFIS 516

  Fly   300 AIGYETN--YRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFYRIYTRLNCENECLAAFLYDTC 362
            :.|.:|.  :|:...........|.:             ..|:...|:...|...|....:.:.|
 Worm   517 SFGLKTKELHRLSAPWGNCSDTFRPV-------------PYIYNEHYSPEGCHRNCFQLKVLEIC 568

  Fly   363 SCIPFDHPLIYSNASIC---SMGDTSCVRRAQRASNRPGW------AKCRQQCLPSCFDLNYLAS 418
            .|.....||.......|   |..|..|:  :...|:..|:      .:|||.|....|:..|.||
 Worm   569 GCGDPRFPLPSEEHRHCNAKSKIDRQCL--SNLTSDSGGYHHLHEQCECRQPCHEKVFETAYSAS 631

  Fly   419 GFSFPLASNNFQLAN---ALVESFNKS-----YLSKNIAVINVYFRESVYYGNTKNAYVGLTEFL 475
            .:    .|.||::..   |:.:.||.:     |..:|.|.|.:|:.:..:....:.|...|....
 Worm   632 AW----PSQNFKIGTDCPAVSDIFNDTEACTEYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLF 692

  Fly   476 SNVGGVMGLFMGFSVISLAE----------ILYFLILKPLAELFVWKRSS----------HVD-S 519
            |:.||.:||::|||||:.||          ::||..:     ::|.|:..          |:| .
 Worm   693 SDFGGNIGLWIGFSVITFAEFAELFCEICKLMYFKGI-----VYVQKKMQGKEYTSSSLMHIDFL 752

  Fly   520 EKSLKHNAFGIEKGQSSDNPSFWHSKELYPK 550
            ::|.|.:..|  :.:.|.|.|   :|||..|
 Worm   753 QRSPKKSQPG--EDEVSTNES---TKELMSK 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	ASC	29..499	CDD:459966	122/689 (18%)
unc-8	NP_001294293.1	deg-1	107..716	CDD:273309	122/680 (18%)