Protein Alignment ppk12 and unc-105

DIOPT Version :10

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001364812.1
• Gene: unc-105 / 174306
• WormBaseID: WBGene00006832
• Length: 974
• Species: Caenorhabditis elegans
• Alignment Length: 747
• Identity: 136/747 - (18%)
• Similarity: 243/747 - (32%)
• Gaps: 262/747 - (35%)

  Fly    27 RQFLNQTSLHGLKFVGDSGLSSWERSFFLGSF---VTALIITVHLISNIYVKWDSTPVIIGISPQ 88
            :.|..|::.||:.....:. ..| |.|:..:|   :.||:|.:..:.:.|.::..| |.:.:..:
 Worm   118 KSFEKQSTFHGISHAATAD-GKW-RWFWYTAFTICLLALLIQIFFLISKYRQYGKT-VDLDLKFE 179

  Fly    89 ATSILKVPFPAITICNMNQVQRSLVA------------NYREGSNE------------------- 122
                 ..|||:|||||:|..::|.:.            :.|.||.:
 Worm   180 -----NAPFPSITICNLNPYKKSAIQSNPNTKAMMEAYSRRIGSGDKTEGIAAALSATGGLHAKV 239

  Fly   123 -------------------SALLKLLCESDSWESSEADEEFSA----SNFVTNNLKISEFVSNHS 164
                               .|..:.||:.:..........|:|    ....|||  .:.|::.|:
 Worm   240 RRAKRKAKGKPRLRDRRYHQAFAQCLCDIEQLTGDRKGSCFAAFKGKIEIDTNN--TAGFMNLHT 302

  Fly   165 QSCERMLLFCRFSAV--------------ERNCS-----------------QLFQQILTDEGLC- 197
            ..|     .|:...|              |:.||                 :|::.|.....||
 Worm   303 SRC-----LCQLDTVSKALWPCFPYSSWKEKLCSECVDNTGHCPMRFYKGNELYENIKEQVDLCL 362

  Fly   198 -------CV--------FNFQPPEYLY-----KPFAN---------------NNRNLTNSDGFES 227
                   ||        ....|.:.|.     |..|:               ....:|.:.|||.
 Worm   363 CHKEYNHCVSTRDDGIILEISPNDELNDLDIGKKIASQLSAQQEKQAEVTTTEAPTVTQALGFEE 427

  Fly   228 VMWD----------------------PESGYPE---------------QLPPKF----------- 244
            :..|                      .||...|               |:...|
 Worm   428 LTDDIAITSQAQENLMFAVGEMSEKAKESMSYELDELVLKCSFNQKDCQMDRDFTLHYDNTFGNC 492

  Fly   245 ----YPATAS----GTGITLGFTAVLDAEMGEYYCSSTNGPGFKVYFHNPIEVPKVKEAGLISAI 301
                |..||.    ..|...|...:|.|.:.| |..:|...||::..|:...||.....|..:..
 Worm   493 YTFNYNRTAEVASHRAGANYGLRVLLYANVSE-YLPTTEAVGFRITVHDKHIVPFPDAFGYSAPT 556

  Fly   302 GYETNYRIEM---VRAEAVPAIRSISRDGRQCLFKNEKELIFYRIYTRLN-----CENECLAAFL 358
            |:.:::.:.|   :|.|....         .|....|....|  :||...     |...|....:
 Worm   557 GFMSSFGVRMKQFIRLEPPYG---------HCRHGGEDAATF--VYTGFQYSVEACHRSCAQKVI 610

  Fly   359 YDTCSCIPFDHP---LIYSNASIC---SMGDTSCVRRAQRASNRPGW-----AKCRQQCLPSCF- 411
            .:.|.|....:|   :..:|...|   :|....|:|      |...|     :|.::..:|.|:
 Worm   611 VEACGCADPMYPVAEMFGNNTKPCQAVNMDQRECLR------NTTLWLGELYSKGKEAIIPDCYC 669

  Fly   412 -----DLNYLASGFSFPLASNNFQLANALVESF--NKSYLSKNIAVINVYFRESVYYGNTKNAYV 469
                 :.||..:..|....|.:.::...|...|  .:.| .||.|::.:::.|..|....::...
 Worm   670 HQPCQETNYEVTYSSARWPSGSAKVMECLPGDFLCLEKY-RKNAAMVQIFYEELNYETMQESPAY 733

  Fly   470 GLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFVWKRSSHVDSEKSLKHNAFGIEKGQ 534
            .||..|:::||:.||::|.||:||.||:..::.  ..:.:|.||...:.::   .|::..:.:..
 Worm   734 TLTSVLADLGGLTGLWIGASVVSLLEIVTLIVF--ATQAYVRKRKGSISAQ---SHHSVPVHRAS 793

  Fly   535 SSDNPSFWHSKELYPKGVSISAYENAKSTKGL 566
            .                ||::....:.:|:.:
 Worm   794 R----------------VSLNTLHKSSTTQSV 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	ASC	29..499	CDD:459966	129/676 (19%)
unc-105	NP_001364812.1	deg-1	119..763	CDD:273309	129/677 (19%)