DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk12 and AgaP_AGAP009590

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_318613.4	Gene:	AgaP_AGAP009590 / 1278964	VectorBaseID:	AGAP009590	Length:	498	Species:	Anopheles gambiae

Alignment Length:	565	Identity:	141/565 - (24%)
Similarity:	228/565 - (40%)	Gaps:	154/565 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FVRSLRQFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWD---STPVII 83
            |.:.||...:.|:|||...:...|.|..||:.:..:.|.:   |:..|:.:.:.|.   .||.:.
Mosquito    14 FGKQLRGLCDITALHGYSQIVRDGYSMVERTVWTCAVVAS---TISAITLLMISWSWSVETPTVT 75

  Fly    84 GISPQATSILKVPFPAITICNMNQVQ----RSLVANYREGSNESALLKLLCESDSWESSEADEEF 144
            ...........:||||:|:||:|::.    ||.....|...|.:.             .|..|.|
Mosquito    76 VTESTNYPTWNLPFPAVTVCNLNKISASAARSRAETMRRPGNMTV-------------DELTEMF 127

  Fly   145 SASNFVT-------------------NNLKISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQI 190
            .....||                   |||:|.:.:...:..|..:|..|.:...:..|..|||.:
Mosquito   128 RLFLHVTGLGDPDPVRYRLLHDIMLMNNLEIPQLIGEFTPPCGTLLERCMWKGTQWRCDNLFQVV 192

  Fly   191 LTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLP---PKFYPATASGT 252
            .:.|||||.||:      |....:|                    ||:::.   || .|.....:
Mosquito   193 NSTEGLCCSFNY------YGLLKDN--------------------YPKKITVSVPK-DPRRVMAS 230

  Fly   253 GITLGFTAVLDAEMGEYYCSSTNGPGFKVYFHNPIEVP------KVKEAGLISAI------GYET 305
            |...|.:.:|.....:|:.:.....||||..|:..:.|      |:..||..|.|      .|.|
Mosquito   231 GYQTGLSILLQPLAEDYHSTDVASYGFKVMIHSSYDYPDNDAEIKLVLAGTESFITLRPTATYAT 295

  Fly   306 NYRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHP 370
            :..:::     .||:|:       |..:.|:.|...:.|:.:||..||.||.:|..|.|:|:..|
Mosquito   296 DDALDV-----APAVRN-------CYSRQERVLGVMQRYSYVNCMVECRAANIYAKCGCVPYHLP 348

  Fly   371 LIYSNASI--CSMGDTSCVRRA---------------QRASNRPGWAKCRQQCLPSCFDLNY--- 415
               :|.|:  |.|.|..||.||               :|.|.....|.|  .|||.|..:.|
Mosquito   349 ---NNGSMRNCEMKDMECVVRARDRYVTAVPTRNGSVERLSYGSVVAPC--GCLPGCDKVQYPSE 408

  Fly   416 LASG-----FSFPLASNNFQLANALVESFNKSYLSKNIAVINVY--------FRESVYYGNTKNA 467
            :.:|     |||          ||:  ||.|....:|.:::::|        ||..:|..:
Mosquito   409 MVTGRMNRSFSF----------NAI--SFFKDIQLQNQSLVHIYLADLTATHFRMDIYQDS---- 457

  Fly   468 YVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLAELFVWK 512
             :|:   |::.||::|||:|||:|:..|::|:..::.|.:....|
Mosquito   458 -LGV---LASFGGILGLFLGFSIITGFEMVYYFSIRLLFDAIAKK 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	135/544 (25%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	135/543 (25%)
AgaP_AGAP009590	XP_318613.4	ASC	22..485	CDD:279230	135/542 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28677
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
TreeFam	0	0.000	Not matched by this tool.
	5	4.830