DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and AgaP_AGAP010430

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_311517.4	Gene:	AgaP_AGAP010430 / 1272617	VectorBaseID:	AGAP010430	Length:	511	Species:	Anopheles gambiae

Alignment Length:	503	Identity:	108/503 - (21%)
Similarity:	195/503 - (38%)	Gaps:	77/503 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSIL 93
            |.:.:.:||:.::.....:.:.|..::...|...:..:.||..::.|:..:|..:.|:.: ..|:
Mosquito    40 FASMSKIHGMYYLQRQVTTGFVRLLWIAIIVAFFVFGIVLIYLLWQKFVDSPTRMTIASE-MKIV 103

  Fly    94 KVPFPAITICNMNQVQRSLVANYRE------GSNESALLKLL-----CESDSWESSEADEEFSAS 147
            :||||.||:|:...|.......:.|      |:.:.::||.|     .....|......:.....
Mosquito   104 QVPFPGITLCHPQSVVDYKAERFVEKIKLPLGATKESVLKNLPSLGYFTEHQWTFPRPQDLRMID 168

  Fly   148 NFV-TNNLKISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQI-----LTDEGLCCVFNFQPPE 206
            |.: .||..|.:.:......||..:|.|.::..:..|......:     .:..|.||.||
Mosquito   169 NVLQLNNYTIEQAIDELGMICEDFILVCYWAGKQFPCFAKHAFLGWIGSTSHYGACCSFN----- 228

  Fly   207 YLYKPFANNNRN--LTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEY 269
              |.|....|::  :.|:.|....:....:|||:          ||            |.:.|..
Mosquito   229 --YHPNVRGNKDPFVVNTYGMHGGLSVIGTGYPQ----------AS------------DGKSGAL 269

  Fly   270 YCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKN 334
            |     ..||.:..|:|.:.........:..:|.||...:....:.....:.::.:..|.|:..:
Mosquito   270 Y-----SEGFMLMIHHPHDFAVEASPLTLIRLGKETFVNVLPTDSRCSEQVLALPQSQRDCIVGS 329

  Fly   335 EKELIFYRIYTRLNCENECLAAFLYDTCSCIPF--DHPLIYSNAS---ICSMGDTSCVRRAQRAS 394
            :......| |.:..|..|||...::..|.|.||  ..|::..|..   .|::.|:.|.     ..
Mosquito   330 DFTPPIER-YRQPACTLECLRNEVHRKCGCHPFHLPRPMVGPNGQGIRNCTVYDSMCF-----VE 388

  Fly   395 NRPGWAKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSYLSKNIA----VINVYF 455
            |...:.:.:..|||||.|:.|..:......::.||        |.|..|...|:.    :.:::.
Mosquito   389 NYYMFKRLQCNCLPSCSDVTYKTASIVSNFSAYNF--------SINPFYKETNLTDFEFIFHIFM 445

  Fly   456 RESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILK 503
            ...|...|.:...|.....|||:||...|.:|.||:||.|:|:|.|.:
Mosquito   446 SNQVVAANRRIVVVSWISLLSNLGGAFSLCLGISVLSLFEVLFFSIFR 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	106/497 (21%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	106/497 (21%)
AgaP_AGAP010430	XP_311517.4	ASC	40..489	CDD:279230	106/497 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D112386at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
TreeFam	0	0.000	Not matched by this tool.
	4	3.820