DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and LOC116411522

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_031759798.1	Gene:	LOC116411522 / 116411522	-ID:	-	Length:	432	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	114/525 - (21%)
Similarity:	196/525 - (37%)	Gaps:	156/525 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPSPSAGTERQGSSLFLLKSFVRSLRQFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITV 66
            ||.||                  .|..|.:.::|||:..|...|..:..|.|:..||:.:|...:
Frog    22 EPKPS------------------DLTVFASNSTLHGISHVFLPGGVTPRRVFWACSFLASLSCFL 68

  Fly    67 HLISNIYVKWDSTPVIIGISPQATSILKVPFPAITICNMNQVQRSLVAN---YREGSNESALLKL 128
            ..:::..:.:.....:..:....:|::|  |||||:||.|..::|.:..   :..|.    ||.:
Frog    69 FQVADRIIFYTEYHHVTTLDEMESSLMK--FPAITLCNYNSFRKSALTRDDLFWVGE----LLGI 127

  Fly   129 LCESDSWESSE-----ADEEFSASNFVTNNLKISEFVSNHSQSCERMLLFCRFSAVERNCS-QLF 187
              |.||.|..|     ||   |...:.:.:..:.||........|.|:|.||:.  .:.|. :.|
Frog   128 --EKDSPEVLEALGIPAD---SGPIYPSKSYNMQEFYERAGHVMEDMMLECRYR--NQECGPENF 185

  Fly   188 QQILTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGT 252
            ..:.|..|.|..||                  :..||:| :::..:.|              :|.
Frog   186 TAVYTRYGKCYTFN------------------SGQDGYE-LLYTLKGG--------------TGN 217

  Fly   253 GITLGFTAVLDAEMGEYY------CSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEM 311
            |:.|    :||.:..||.      ..::...|.||..|:..|.|.:.:.|...|.|::|....:.
Frog   218 GLEL----MLDIQQDEYLPVFGETDETSLEAGVKVQIHSQEEPPFIDQLGFGVAPGFQTFVSCQQ 278

  Fly   312 VRAEAVPAIRSISRDGRQCLFKNEK-ELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHPLIYSN 375
            .....:|      |....|  ::|. :..::|.|:...|..:|.:.::.:.|.|.....|   .|
Frog   279 QELVYLP------RPWGDC--RSEPLDSPYFRTYSITACRIDCESRYIVEKCKCRMVHMP---GN 332

  Fly   376 ASICS----------------------MGDTSCVRRAQRASNRPGWAKCRQQCLPSCFDLNYLAS 418
            |::||                      :.||.|  |..|........|     :||.....|||
Frog   333 ATVCSPDQYKCADIQLDFLVEEDNTFCVCDTPC--RTVRYGKELSMVK-----IPSKASARYLA- 389

  Fly   419 GFSFPLASNNFQLANALVESFNKS--YLSKNIAVINVYFRESVYYG--NTKNAYVGLTEFLSNVG 479
                              ..:||:  |:::||.|::::| |::.|.  ..|.||        .:.
Frog   390 ------------------RKYNKTEQYIAENILVLDIFF-EALNYETIEQKKAY--------EMA 427

  Fly   480 GVMGL 484
            |::||
Frog   428 GLLGL 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	109/499 (22%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	109/498 (22%)
LOC116411522	XP_031759798.1	ASC	28..431	CDD:413546	108/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5830
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I4647
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48391
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050