DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and scnn1gl

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_017947701.2	Gene:	scnn1gl / 101734161	XenbaseID:	XB-GENE-22061126	Length:	481	Species:	Xenopus tropicalis

Alignment Length:	530	Identity:	120/530 - (22%)
Similarity:	203/530 - (38%)	Gaps:	142/530 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 KVPFPAITICNMNQVQRSLVANYREGSNESALLKLLCESDSWESSEADEEFSASN-------FVT 151
            ::||||||.||:|:.:.|.:        .|:..:.|.|..|:.|....||.|.|:       |..
Frog    28 RLPFPAITFCNLNRARMSKL--------NSSKYQSLTEYLSFTSGNESEEGSISHGRDRNFTFAL 84

  Fly   152 NNLKISEFVSNHSQSCERMLLFCRFSAVERNCSQ-LFQQILTDE-GLCCVF------------NF 202
            :.|...|.:....| .|.||:.|.|.  :..|:: .|...|..: |:|..|            |:
Frog    85 SQLTPQEQMELGHQ-LENMLISCIFH--DEVCNESFFTPFLNPKLGICYTFNGRRQADLQHWQNY 146

  Fly   203 QPPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMG 267
            |..|||                                       .|:..|.:.|.|..|..|..
Frog   147 QQEEYL---------------------------------------NATKAGFSYGLTMELFIEQS 172

  Fly   268 EYYCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPA-----------IR 321
            ||..|.:...|.:|..|...::|..::.|:....|.|::..|..|..:.:..           ||
Frog   173 EYISSLSTTAGLRVVLHGQGKMPFPEDEGVNVPPGQESDIGIVKVHVKRLQEPYSSKCSNGNDIR 237

  Fly   322 SISRDGRQCLFKNEKELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHP-LIYSNASICSMGDTS 385
            :...|            ::...|:|..|:..|..|.:...|.|..::.| ...||..:|::.:.|
Frog   238 NFYTD------------VYGTDYSRETCKKSCAQAKMIKNCGCRMWEFPEPPGSNVPLCNISEPS 290

  Fly   386 ---CVRRAQ-RASNRPGWAKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSYLSK 446
               ||...: :.|:......|..||....|:|.         |:|:.:. ::..::||.|...|:
Frog   291 VNHCVEMYEYKLSHDQLKCHCPLQCEEEIFELT---------LSSSQWP-SSMYLDSFTKRLQSR 345

  Fly   447 -----------NIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFL 500
                       |:..:.||:::..|....:...:.|.:..|::||::||::|.||.::||.|. |
Frog   346 KGFQSAQSIRDNVVKVVVYYQQLNYELIEEVPSMQLVDLFSSIGGLVGLWIGVSVCTVAEFLE-L 409

  Fly   501 ILKPLAELFVWKRSSHVDSEKSLK---------HNAFGIEKGQSSDNPSFWHSKELYPKGVSISA 556
            ||..|.  ||.::.|:.:.|....         .:.|..|..||      |.|.:    .||...
Frog   410 ILNLLT--FVIRQISNQEEESPANPYTIPGPEVQSPFSAEHCQS------WTSVD----DVSCLL 462

  Fly   557 YENAKSTKGL 566
            ..|::|::.:
Frog   463 GNNSESSQNM 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	102/452 (23%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	102/452 (23%)
scnn1gl	XP_017947701.2	ASC	1..450	CDD:413546	112/496 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010