Protein Alignment ppk12 and asic5

DIOPT Version :10

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 135/527 - (25%)
• Similarity: 209/527 - (39%)
• Gaps: 118/527 - (22%)

  Fly    16 LFLLKSFVRSLRQ-------FLNQTSLHGLKFV---GDSGLSSWERSFFLGSFVTALII------ 64
            |:|.|..|.||.:       |...||.||:..:   |.||.:|..|:....|.|:..||
 Frog   367 LYLRKHSVPSLEERKKYNHGFATSTSFHGVHNLVENGGSGKNSKFRTAIWTSVVSVFIIMACWQV 431

  Fly    65 TVHLISNIYVKWDSTPVIIGISPQATSILKVPFPAITICNMNQVQRSLVAN----YREGSNESAL 125
            ...:|:  |..|.:|     .|.....:..:.|||||.||:|:.|...|.|    :...:..||:
 Frog   432 CTRVIN--YFSWPTT-----TSVNVQYVENIDFPAITFCNLNRFQTKAVNNLSIAFFLWNIVSAV 489

  Fly   126 LKLL-CESDSWESSEADEEFSASNFVTNNLKISEFVSNHSQSCER-MLLFCRFSAVERNC-SQLF 187
            |... ..||..|..|..:...    :..|..|.||..|:...... .||.|.|....  | .:.|
 Frog   490 LHFTSIASDPGEMQEVTDFLK----LNKNFSIKEFTKNYGFYLNNSTLLKCSFFGYP--CYPEDF 548

  Fly   188 QQILTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFESVMWD-PESGYPEQLPPKFYPATASG 251
            :.|.|:.|.|..||       |...:.|.|..|...|. ||::| .::.:.::      |
 Frog   549 EHIFTEYGNCYTFN-------YNTVSMNKRITTAGRGL-SVLFDIKQTEFTDE------P----- 594

  Fly   252 TGITLGFTAVLDAEMGEYYCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEA 316
               :|||   :||             |.....|:|:..|:....||.|..|...:  :.|.|.:.
 Frog   595 ---SLGF---VDA-------------GISFVLHSPLVPPRFDGLGLHSPAGMHAH--VSMRRFKT 638

  Fly   317 V----------PAIRSISRDGRQCLFKNEKELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHPL 371
            |          |:::                |.::.||:...|..||.:.::.:.|.||||   |
 Frog   639 VIQEHPWGECNPSLK----------------LKYHEIYSTYGCLQECKSYYIQNECGCIPF---L 684

  Fly   372 IYSNASICSMGDT-SCVRRAQ---RASNRPGWAKCRQQCLPSCFDLNYLA--SGFSFPLASNNFQ 430
            :..|...|.:... :||.||.   ..|...........|...|.:.::.|  |..:||    :.:
 Frog   685 LPGNGKECDLQQLYNCVSRALYTIEKSELCSMGTYNSTCPVPCEETDFPATISYSTFP----SDK 745

  Fly   431 LANALVESFNKS--YLSKNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISL 493
            .|..|....:||  |:..|:..|::.:.|..|....:...:..:|.|||:||.:|||.|.|:|::
 Frog   746 AAQFLSAKLSKSALYMRNNLVYIDIKYHEMNYKIMKQQKALTASELLSNIGGQLGLFCGASMITI 810

  Fly   494 AEILYFL 500
            .|:|.:|
 Frog   811 IEVLEYL 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	ASC	29..499	CDD:459966	128/504 (25%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410
		Peptidase_C1A	158..360	CDD:239068
		ASC	387..816	CDD:459966	128/504 (25%)