DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and zdhhc23b

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001003757.1	Gene:	zdhhc23b / 445301	ZFINID:	ZDB-GENE-040808-13	Length:	425	Species:	Danio rerio

Alignment Length:	177	Identity:	47/177 - (26%)
Similarity:	77/177 - (43%)	Gaps:	44/177 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NWRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVY--AL 151
            ||  |..|:.:.|.|:.||:.|.||:|:.||||::...|:||.|||.|:..:.:..:.|::  :|
Zfish   247 NW--CAVCKVVRPRRAGHCRICGVCVLRLDHHCVWINSCVGLANHRTFLLTLLFFLLTSIFGISL 309

  Fly   152 VYNSI-----------YMWVIHGHIYSNWVTVLKLACPML-HLVTGSFWTNMYLVFYSLNILALA 204
            |..|:           |.    ..:||.:.:.|...|... .:|||..          |::|.|.
Zfish   310 VLASVCPDQRVLTALFYC----PDVYSQYSSALCFTCAWYSSIVTGGL----------LHLLLLQ 360

  Fly   205 YGVLLLAYHVPIVLRGGVSADRTKESKEK----------YDRGVYQN 241
                :|...:.:..|....|.|.|.::.:          |.||.:.|
Zfish   361 ----ILNISLNVTEREARLALREKSAQRRLWGLIVHTGHYSRGFWSN 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	37/140 (26%)
zdhhc23b	NP_001003757.1	7TMR-DISM_7TM	<62..179	CDD:284997
zdhhc23b	NP_001003757.1	zf-DHHC	<244..>350	CDD:303066	32/108 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810