DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and CG4676

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_610853.1	Gene:	CG4676 / 36465	FlyBaseID:	FBgn0033815	Length:	284	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	121/265 - (45%)
Similarity:	170/265 - (64%)	Gaps:	6/265 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PSRMVDILCFLIIAVFLPVVFMFEIVVVLPAFHEPGGFFHTFTFLMAMFLVFNIKGNMIACMMID 73
            |..:.|..|||::|||:||.::|.:.:|:|.....||.::|..:|.::||:|||..||:|||::|
  Fly    12 PRSISDFACFLLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLWLASLFLIFNITSNMLACMLVD 76

  Fly    74 TSVNVKKVEPPSD--QL-NWRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRF 135
            ||:..:.::||.|  || .|..|.:||.|.|||||||:.|.||:|||||||.:|.||||..|:|:
  Fly    77 TSIRKELLKPPLDAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRY 141

  Fly   136 FMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKLACPMLHLVTGSFWTNMYLVFYSLNI 200
            |..::.|:.:||:.|.:..|||:|.:|..||..|.|:..:..|::.|:....|.:.|||.|.|.:
  Fly   142 FFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIFAPVVSLMLSPSWESFYLVIYDLTL 206

  Fly   201 LALAYGVLLLAYHVPIVLRGGVSADRTKESKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDLPE 265
            |..|...|||.:|..|...|.|:.:|   ...|||||:..||..|.|.||||.||||.:|||||.
  Fly   207 LGFAISSLLLVFHWSIFKSGSVTRER---GTRKYDRGLRGNLEMVLGKRMHLTWLSPFLRSDLPH 268

  Fly   266 DGYHW 270
            ||.:|
  Fly   269 DGMNW 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	57/126 (45%)
CG4676	NP_610853.1	zf-DHHC	99..232	CDD:279823	59/132 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469527
Domainoid	1	1.000	92	1.000	Domainoid score	I7574
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	1	1.000	-	-		H41720
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4533
Isobase	1	0.950	-	0	Normalized mean entropy	S3153
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D423262at33208
OrthoFinder	1	1.000	-	-		FOG0002152
OrthoInspector	1	1.000	-	-		otm26486
orthoMCL	1	0.900	-	-		OOG6_108577
Panther	1	1.100	-	-	P	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5808
SonicParanoid	1	1.000	-	-		X1251
	14	13.780