DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and zdhhc8b

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_840089.2	Gene:	zdhhc8b / 352941	ZFINID:	ZDB-GENE-030407-3	Length:	751	Species:	Danio rerio

Alignment Length:	298	Identity:	67/298 - (22%)
Similarity:	112/298 - (37%)	Gaps:	89/298 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IIAVFLPVVFMFEIV-VVLPAFHEPGGFFHT-------FTFLMAMFLVFNIKGNMIACMMIDTSV 76
            ::.::..:||:|.:. ..:..|.:||.|...       ..|...::....|||..:
Zfish    46 VVPLYNGIVFLFVLANFSMATFMDPGVFPRADEDEDKDDDFRAPLYKNVEIKGIQV--------- 101

  Fly    77 NVKKVEPPSDQLNWRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIF 141
                      ::.|  |..|....|||..||..|..|:.:.||||.:...|||.||:|:|..|:.
Zfish   102 ----------RMKW--CATCHFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLL 154

  Fly   142 YLFVGSVYALVYNSIYMWVIHGHIYS----NWVTVLKLACPMLHLVTGSFWTNMYLVFYSLNILA 202
            .|.|..|....:..::|  :| |:.:    :....|.:.|     |||.|:         :.::.
Zfish   155 SLSVHMVGVFSFGLLFM--LH-HLETLSALHTTVTLVVMC-----VTGLFF---------IPVMG 202

  Fly   203 LAYGVLLLAYHVPIVLRGGVSADRTKESKEKYDRGVYQNLRSVFGNRMHLAWLSPL--------- 258
            |.      .:|:.:|.||..:   .::...|:..||....|...||..|:. .|||
Zfish   203 LT------GFHMVLVARGRTT---NEQVTGKFRGGVNPFTRGCGGNVKHVL-CSPLAPRYIADPR 257

  Fly   259 -----------IRSDL---------PEDGYHWNVPTNK 276
                       :|.||         .::|.|.|:..:|
Zfish   258 KKIPVTVTPPFLRPDLSNRHISVKVSDNGIHSNILRSK 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	36/130 (28%)
zdhhc8b	NP_840089.2	zf-DHHC	99..224	CDD:279823	39/171 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..346		1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	437..461
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	633..659
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	666..685
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	703..736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810