DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001013141.1	Gene:	Zdhhc4 / 304291	RGDID:	1308389	Length:	343	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	58/260 - (22%)
Similarity:	94/260 - (36%)	Gaps:	58/260 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 CFLIIAVFLPVVFMFEIVVVLPAFHEPGGFFHTFTFLMAMFLVFNIKGNMIACMMIDTSVNVKKV 81
            |.|:..|.|.|..:|   ..|.....||....|...|:.....|:                  :|
  Rat   100 CLLLPYVLLSVNLVF---FTLTCSTNPGTITKTNVLLLLQVYEFD------------------EV 143

  Fly    82 EPPSDQLNWRECGECQKLAPPRSWHCKACKVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVG 146
            ..|.:.    .|..|....|.||.||:.|..|:.:.||||::...|||..|..:|:.::..|...
  Rat   144 MFPKNS----RCSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLLTLTAS 204

  Fly   147 SVYALVYNSIYM--WVIHGHIYSNWVTVLKLACPMLHLVTGSFWTNMYLVFYSLNILALAYGV-- 207
            :....:.::.::  .|...::|..  |.|........:.||....:::|.|..: |..|.:.:
  Rat   205 AATIAILSAAFLLRLVAVSNLYQE--TYLDDLGRFQAVDTGFLIQHLFLAFPRI-IFLLGFVIVL 266

  Fly   208 -LLLAYHVPIVLRGGVSADRTKE-------------------SKEK------YDRGVYQNLRSVF 246
             ||||.::...|....:...|.|                   |.|.      |..|::.||:.||
  Rat   267 SLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHWPLVAWSPSAEPQIHQNIYSHGLWSNLQEVF 331

Fly 247 246
Rat 332 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	34/131 (26%)
Zdhhc4	NP_001013141.1	zf-DHHC	151..292	CDD:279823	36/143 (25%)
Zdhhc4	NP_001013141.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910