DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10344 and ZDHHC22

DIOPT Version :9

Sequence 1:NP_611671.1 Gene:CG10344 / 37565 FlyBaseID:FBgn0034729 Length:278 Species:Drosophila melanogaster
Sequence 2:NP_001351101.1 Gene:ZDHHC22 / 283576 HGNCID:20106 Length:263 Species:Homo sapiens


Alignment Length:288 Identity:74/288 - (25%)
Similarity:117/288 - (40%) Gaps:82/288 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 RMVDILC---FLIIAVFLPVVFMFEIVVVLPAFHE-PG-------GFFHTFTFLMAMFLVFNIKG 64
            |:::::.   ||.|::   |.|:.::.:.||:..| |.       ...|...||   ||..|..|
Human     5 RLLNVVAPAYFLCISL---VTFVLQLFLFLPSMREDPAAARLFSPALLHGALFL---FLSANALG 63

  Fly    65 NMIACMMIDTSVNVKKVEPPSDQLNWRECGECQKLA------PPRSWH-CKACKVCILKRDHHCI 122
            |.:  ::|..|        |.|      .|.||..:      |..|.| |:.|....|:.||||.
Human    64 NYV--LVIQNS--------PDD------LGACQGASARKTPCPSPSTHFCRVCARVTLRHDHHCF 112

  Fly   123 YTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKLACPMLHLVTGSF 187
            :||.|||.||.|.|:.|..|..:..:|::|         .|..|.:.|..:..|.|:..|   :.
Human   113 FTGNCIGSRNMRNFVLFCLYTSLACLYSMV---------AGVAYISAVLSISFAHPLAFL---TL 165

  Fly   188 WTNMYLVFYSLNILALAYGVLLLAY---------------HVPIVLRGGVSADRTKESKEKYDRG 237
            .......|:|..:|.....|:|:.|               .:.::|||        :::.:..:|
Human   166 LPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRG--------QTRHQVRKG 222

  Fly   238 V-------YQNLRSVFGNRMHLAWLSPL 258
            |       .:||:.|||.|..|..|.|:
Human   223 VAVRARPWRKNLQEVFGKRWLLGLLVPM 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10344NP_611671.1 zf-DHHC 93..220 CDD:279823 39/148 (26%)
ZDHHC22NP_001351101.1 DHHC 92..218 CDD:366691 37/145 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S3153
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR22883
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.860

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