DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and dhhc-8

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001370072.1	Gene:	dhhc-8 / 176731	WormBaseID:	WBGene00012718	Length:	471	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	58/247 - (23%)
Similarity:	93/247 - (37%)	Gaps:	80/247 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 IAVFLPVVFMFEIVV---------VLP----AFHEPGGFFHTFTFLMA----MFLVFNIKGNMIA 68
            |:..||....:.:::         :.|    .:|.||      ..|:|    :||:  :..|::.
Worm     5 ISALLPAAIAWALIIGCSVSFFWFIAPQIWNQWHTPG------LILIAIDVVLFLM--VSSNLLM 61

  Fly    69 CMMIDTSVNVKKV--EPPSD-------------------QLNWRECGECQKLAPPRSWHCKACKV 112
            .|::|.:|:...:  |.|:.                   ::.|  |..|:...||||.||..|..
Worm    62 AMLLDPAVHPYAIGSEEPTQVDDLRAPLYKNVDINGITVRMKW--CVTCKFYRPPRSSHCSVCNR 124

  Fly   113 CILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWV-----IHGHIYSN---W 169
            ||...||||.:...|:|.||:|:|..|:..|.:..:|.......|:|.     ...||.|.   .
Worm   125 CIETFDHHCPWVHNCVGKRNYRYFFFFLCSLSIHMMYVFFLCFAYVWSGSDTNARDHILSPPYLC 189

  Fly   170 VTVLKLACPMLHL-VTGSFWTNMYLVFYSLNILALAYGVLLLAYHVPIVLRG 220
            ..||...|.:|.: |.|                       |..:|:.:|.||
Worm   190 AIVLLALCAVLCVPVIG-----------------------LTVFHLVLVARG 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	38/135 (28%)
dhhc-8	NP_001370072.1	DHHC	98..228	CDD:396215	41/146 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810