DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10344 and ZDHHC15

DIOPT Version :9

Sequence 1:	NP_611671.1	Gene:	CG10344 / 37565	FlyBaseID:	FBgn0034729	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_659406.1	Gene:	ZDHHC15 / 158866	HGNCID:	20342	Length:	337	Species:	Homo sapiens

Alignment Length:	299	Identity:	71/299 - (23%)
Similarity:	127/299 - (42%)	Gaps:	71/299 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VDILCFLIIAVFLPVVFMFEI-----------VVVLPAFHEPGGFFHTFTFLMAMFLV------- 59
            |.:|..:::.::....::||:           |:.|..:|....|| |:|:..::|.:
Human    23 VPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFF-TWTYWKSIFTLPQQPNQK 86

  Fly    60 FNI------------KGNMIACMMIDTSVNVKK--VEPPSDQLNWRECGECQKLAPPRSWHCKAC 110
            |::            :..:...|::|.:   ||  |...:.....|.|..|..:.|.|..||..|
Human    87 FHLSYTDKERYENEERPEVQKQMLVDMA---KKLPVYTRTGSGAVRFCDRCHLIKPDRCHHCSVC 148

  Fly   111 KVCILKRDHHCIYTGCCIGLRNHRFFMGFIFYLFVGSVYALVYNSIYMWVIHGHIYSNWVTVLKL 175
            .:|:||.||||.:...|||..|::||:.|           |.|:.:|...|...::|.::...:.
Human   149 AMCVLKMDHHCPWVNNCIGFSNYKFFLQF-----------LAYSVLYCLYIATTVFSYFIKYWRG 202

  Fly   176 ACPML----HLVTGSFWTNMYLVFYSLNILALAYGVLLLAYHVPIVLRGGVSAD-------RTKE 229
            ..|.:    |::...|...|:  |.||        |:|..||..:|.|...:.:       .:..
Human   203 ELPSVRSKFHVLFLLFVACMF--FVSL--------VILFGYHCWLVSRNKTTLEAFCTPVFTSGP 257

  Fly   230 SKEKYDRGVYQNLRSVFGNRMHLAWLSPLIRSDLPEDGY 268
            .|..::.|..:|::.|||::... ||.|:..|  |.||:
Human   258 EKNGFNLGFIKNIQQVFGDKKKF-WLIPIGSS--PGDGH 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10344	NP_611671.1	zf-DHHC	93..220	CDD:279823	38/130 (29%)
ZDHHC15	NP_659406.1	zf-DHHC	<126..308	CDD:327686	53/192 (28%)
ZDHHC15	NP_659406.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810