DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr58E-2 and Sf1

DIOPT Version :9

Sequence 1:	NP_001286724.1	Gene:	qkr58E-2 / 37562	FlyBaseID:	FBgn0022985	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001104261.1	Gene:	Sf1 / 22668	MGIID:	1095403	Length:	639	Species:	Mus musculus

Alignment Length:	407	Identity:	95/407 - (23%)
Similarity:	150/407 - (36%)	Gaps:	112/407 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NADGEKAQPAPAVQKYMQELMTERSRMENHFPLAVKLIDE----ALERVQLNGRIPTRDQYADVY 121
            |.:.....|.|......:.|.|...|...      ||.:|    ..|.|.||   |.....|| |
Mouse    75 NPEDRSPSPEPIYNSEGKRLNTREFRTRK------KLEEERHTLITEMVALN---PDFKPPAD-Y 129

  Fly   122 QQRTIKLSQKVHVPIKDK--KFNYVGKLLGPKGNSLRRLQEETQCKIVILGRFSMKD---RAREE 181
            :....::|.||.:| :|:  :.|:||.|:||:||:|:.:::|...||:|.|:.|:|:   ..::.
Mouse   130 KPPATRVSDKVMIP-QDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDG 193

  Fly   182 ELRNSADAKYAHLNLPLHVEVSTIAPPAEAYARVAYALAEIRRYL-----TPDKHDDIRQEQYRE 241
            ::....|.       |||..|:     |.....|..|:.:||..|     ||:..:|:|:.|.||
Mouse   194 QMLPGEDE-------PLHALVT-----ANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRE 246

  Fly   242 LM--------EDPEAAKKLTLRQLQQQSNAAASGAGGGGGGGGGNGNGGAAGSGSNNGNGNQRSG 298
            |.        :|....:.....:.:..:|.......||.|....:
Mouse   247 LARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASD-------------------- 291

  Fly   299 GNYRQKFQQ-------QSHYRHNEETVYFRSHNNAYHQPKPYVPAAQRGNAMHTTLP----PQAI 352
                .|||:       |...|.::|  |..........|   |||:....:...|.|    |:..
Mouse   292 ----CKFQRPGDPQSAQDKARMDKE--YLSLMAELGEAP---VPASVGSTSGPATTPLASAPRPA 347

  Fly   353 VRAS---PPGMVVSAAS--------------FNGRNAGLGNAGGGG--IMANSIVATTGGGIG-- 396
            ..||   ||.::.:..|              ::|.:.|.....|||  ...:.:.:.|||..|
Mouse   348 APASNPPPPSLMSTTQSRPPWMNSGPSENRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHP 412

  Fly   397 ------GAVPPNMRYRP 407
                  |..||.|:..|
Mouse   413 MQHNPNGPPPPWMQPPP 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr58E-2	NP_001286724.1	SF1_like-KH	129..244	CDD:239088	40/132 (30%)
Sf1	NP_001104261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		Nuclear localization signal. /evidence=ECO:0000255	15..19
		MSL5	17..257	CDD:227503	57/204 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..94		3/18 (17%)
		ZnF_C2HC	278..293	CDD:197667	3/38 (8%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..584		25/105 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810