DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment qkr58E-3 and khdrbs2

DIOPT Version :9

Sequence 1:	NP_001246460.1	Gene:	qkr58E-3 / 37559	FlyBaseID:	FBgn0022984	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001070758.1	Gene:	khdrbs2 / 768147	ZFINID:	ZDB-GENE-061013-497	Length:	346	Species:	Danio rerio

Alignment Length:	280	Identity:	96/280 - (34%)
Similarity:	145/280 - (51%)	Gaps:	59/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KFLADLDEERQRLSADFPLCALLIDEAVDRVYCTGRIPGKEF--------YADVYKQKPMKITQK 83
            |:|.:|..|::.|.|.|.....|:.|.::      :..|.|.        |.|:...|.:|::::
Zfish     5 KYLPELVAEKESLDASFVHAMRLLAEEIE------KFEGDELRKDGEVKKYLDIISNKNIKLSER 63

  Fly    84 VFVPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIRDRNKEEQLRSTGDPRYAHLQ 148
            |.:||:|||||||.||:|||:|||::||||||..|::|.|:.|:||:.|||:||.:|:.:||||.
Zfish    64 VLIPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLS 128

  Fly   149 KDLFLEVSTVATPAECYARIAYALAEIRKYLIPDKNDEVSHEQLRELMEM----DPESAKNIHGP 209
            .||.:.:...|.|.|.|:|:::||.||:|:|:||.|||:..||||||..:    ||...::..|.
Zfish   129 NDLHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSDDPSRGRSARGR 193

  Fly   210 NLEAYRSVFDKKFGGNSNGAPKYINLIKRAAENPPEVDDVEEVAYEYEHRMPPKRPPTGYEYSKP 274
            .|..           .|..:|:     .|.:..||                    .|.|...:.|
Zfish   194 GLRL-----------TSTASPR-----GRGSAAPP--------------------APPGRGAAAP 222

  Fly   275 RPSI-----IPTNAAAYKRP 289
            |.::     :||.|.....|
Zfish   223 RGTVSSRTSVPTPARGVSAP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
qkr58E-3	NP_001246460.1	SF1_like-KH	81..200	CDD:239088	64/122 (52%)
khdrbs2	NP_001070758.1	Qua1	6..57	CDD:292891	12/56 (21%)
		SF1_like-KH	61..180	CDD:239088	64/118 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..292		18/104 (17%)
		Sam68-YY	<281..>306	CDD:293176
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.810