DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment babos and PAPLN

DIOPT Version :9

Sequence 1:	NP_001286719.1	Gene:	babos / 37557	FlyBaseID:	FBgn0034724	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_001352835.1	Gene:	PAPLN / 89932	HGNCID:	19262	Length:	1278	Species:	Homo sapiens

Alignment Length:	189	Identity:	36/189 - (19%)
Similarity:	70/189 - (37%)	Gaps:	30/189 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LIAGLLLIVGSAAVISYPQSSMDDDQMQADDDFDYGGEDQSAPSPQTKSPNPVASEKI----NKT 68
            :|.|.:.::..|.:..:||        ..|...|:|....:.|.....|.:|..:.::    |:.
Human   994 IIGGDMAVLSEAELSRFPQ--------PRDPAQDFGQAGAAGPLGAIPSSHPQPANRLRLDQNQP 1050

  Fly    69 LSVTGIRGEDVVLKCDVGSNLHSSDVVVLWYFGDNVISNGKNLVQPNFKLDANYDLTILKASPQV 133
            ..|....|:.:.:.|....   .....:.|.      .:|:.:..|..:|..:..|.|.:.:.:.
Human  1051 RVVDASPGQRIRMTCRAEG---FPPPAIEWQ------RDGQPVSSPRHQLQPDGSLVISRVAVED 1106

  Fly   134 AGSYLCKVLPSGS-----VVNTKVTIAEHSLDAIAPESSTSAAGSASSFLGCTVLASTV 187
            .|.|.| |..:|.     .|..:| :.|.::..: |.:.|...|..:..| |.|...:|
Human  1107 GGFYTC-VAFNGQDRDQRWVQLRV-LGELTISGL-PPTVTVPEGDTARLL-CVVAGESV 1161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
babos	NP_001286719.1	ig	70..154	CDD:278476	16/88 (18%)
babos	NP_001286719.1	IG_like	70..154	CDD:214653	16/88 (18%)
PAPLN	NP_001352835.1	TSP1	29..80	CDD:214559
		ADAM_spacer1	183..298	CDD:310520
		TSP1	308..361	CDD:214559
		TSP1	369..424	CDD:214559
		TSP1	424..481	CDD:214559
		TSP1	488..539	CDD:214559
		Kunitz_BPTI	753..805	CDD:278443
		Papilin_u7	814..905	CDD:318767
		Ig	914..>978	CDD:325142
		I-set	1049..1119	CDD:254352	14/79 (18%)
		IG	1139..1219	CDD:214652	7/24 (29%)
		PLAC	1235..1267	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900