DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment babos and KIRREL3

DIOPT Version :9

Sequence 1:	NP_001286719.1	Gene:	babos / 37557	FlyBaseID:	FBgn0034724	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	XP_011541328.1	Gene:	KIRREL3 / 84623	HGNCID:	23204	Length:	809	Species:	Homo sapiens

Alignment Length:	158	Identity:	32/158 - (20%)
Similarity:	57/158 - (36%)	Gaps:	33/158 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DFDYGGEDQSAPSPQTKSPNPVASEKINKTLSV-TGIR------------GEDVVLKCDVGSNLH 90
            |:.|..|..|.     :..|.:.|..:::|:.| .|.|            |.|.:..|....|
Human   310 DYTYFSEPVSC-----EVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGN-- 367

  Fly    91 SSDVVVLWYFGDNVISNGKNLVQPNFKLDANYDLTILKASPQVAGSYLCK-VLPSGSVVNTKVTI 154
             ..:.::|      :..|..:|..|.|     .||:.....:.||.|:|: |:|.......:||:
Human   368 -PSLTIVW------MKRGSGVVLSNEK-----TLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTL 420

  Fly   155 AEHSLDAIAPESSTSAAGSASSFLGCTV 182
            ..:....|:...:..|.......:.|.:
Human   421 TVNGPPIISSTQTQHALHGEKGQIKCFI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
babos	NP_001286719.1	ig	70..154	CDD:278476	21/97 (22%)
babos	NP_001286719.1	IG_like	70..154	CDD:214653	21/97 (22%)
KIRREL3	XP_011541328.1	Ig	58..149	CDD:299845
		IG_like	60..149	CDD:214653
		I-set	156..249	CDD:254352
		Ig2_KIRREL3-like	171..252	CDD:143236
		Ig_2	260..337	CDD:290606	7/31 (23%)
		I-set	341..422	CDD:254352	20/94 (21%)
		IGc2	355..406	CDD:197706	15/64 (23%)
		Ig5_KIRREL3	424..521	CDD:143306	3/25 (12%)
		IG_like	432..521	CDD:214653	2/17 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900