DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment babos and Sdk2

DIOPT Version :9

Sequence 1:	NP_001286719.1	Gene:	babos / 37557	FlyBaseID:	FBgn0034724	Length:	196	Species:	Drosophila melanogaster
Sequence 2:	NP_766388.2	Gene:	Sdk2 / 237979	MGIID:	2443847	Length:	2176	Species:	Mus musculus

Alignment Length:	191	Identity:	47/191 - (24%)
Similarity:	69/191 - (36%)	Gaps:	43/191 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RTD--LLIAGLLLIVGSAAVISYPQSSMDDDQMQADDDFDYGGEDQSAPSPQTKSPNPVASEKIN 66
            |:|  |.|:|||               .||..|......:..||.|::......|   :|.....
Mouse   364 RSDGGLQISGLL---------------PDDTGMLQCFAHNAAGEAQTSTYLAVTS---IAPNITR 410

  Fly    67 KTLSVTGIRGEDVVLKCDVGSNLHSSDVVVLWYFGDNVISNGKNLVQ-PNFKLDANYDLTILKAS 130
            ..|..|.|.|..|||.|:...   :....:.|..|:.::::|.  || |.|.|..:..|.|....
Mouse   411 GPLDSTVIDGMSVVLACETSG---APRPAITWQKGERILASGS--VQLPRFTLLESGSLLISPTH 470

  Fly   131 PQVAGSYLCKVLPSGSVVNTKVTIAEHSLDAIA---------PESSTSAAGSASSFLGCTV 182
            ...||:|.|....|..|       .|.|.|.:.         |:..:...|:.:|.: |.|
Mouse   471 ISDAGTYTCLATNSRGV-------DEASADLVVWARTRITKPPQDQSVIKGTQASMV-CGV 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
babos	NP_001286719.1	ig	70..154	CDD:278476	23/84 (27%)
babos	NP_001286719.1	IG_like	70..154	CDD:214653	23/84 (27%)
Sdk2	NP_766388.2	IG_like	44..113	CDD:214653
		IGc2	44..102	CDD:197706
		IG_like	124..207	CDD:214653
		Ig	136..192	CDD:299845
		IG_like	226..308	CDD:214653
		IGc2	237..290	CDD:197706
		I-set	312..401	CDD:254352	13/51 (25%)
		Ig	330..398	CDD:143165	13/48 (27%)
		I-set	406..496	CDD:254352	27/101 (27%)
		Ig	420..496	CDD:299845	24/87 (28%)
		Ig	506..590	CDD:299845	5/19 (26%)
		IG_like	506..590	CDD:214653	5/19 (26%)
		FN3	594..685	CDD:238020
		FN3	697..790	CDD:238020
		FN3	798..894	CDD:238020
		FN3	899..987	CDD:238020
		FN3	997..1091	CDD:238020
		FN3	1103..1198	CDD:238020
		FN3	1205..1294	CDD:238020
		FN3	1305..1398	CDD:238020
		FN3	1404..1488	CDD:238020
		FN3	1507..1620	CDD:238020
		FN3	1630..1723	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1712..1734
		FN3	1728..1809	CDD:238020
		FN3	1841..1920	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2013..2032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2043..2070
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2102..2176
		PDZ-binding. /evidence=ECO:0000269\|PubMed:20219992	2170..2176
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900