DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13506 and PAPLN

DIOPT Version :9

Sequence 1:NP_001286718.1 Gene:CG13506 / 37556 FlyBaseID:FBgn0034723 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_001352835.1 Gene:PAPLN / 89932 HGNCID:19262 Length:1278 Species:Homo sapiens


Alignment Length:359 Identity:85/359 - (23%)
Similarity:131/359 - (36%) Gaps:85/359 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 AEQEAPPYFD---------VTDLRVEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQNPIS 119
            |...|||:..         |....|:|..|..|.|:|.......|.| .|.|      :||...|
Human   895 AGSPAPPFHSSSYRISLAGVEPSLVQAALGQLVRLSCSDDTAPESQA-AWQK------DGQPISS 952

  Fly   120 QRVQCMLNNSILLRNVSPEDSDDYYC-EILPQRVRQHTALR-VGARLSILCDDRDIT------DR 176
            .|.:...:.|:::..:..||:..|.| ...|.|..|...|| :|..:::| .:.:::      |.
Human   953 DRHRLQFDGSLIIHPLQAEDAGTYSCGSTRPGRDSQKIQLRIIGGDMAVL-SEAELSRFPQPRDP 1016

  Fly   177 SQTFRQ-----------------------------------GDHHKLECRTYLPDNATIKWSFND 206
            :|.|.|                                   |...::.||........|:|   .
Human  1017 AQDFGQAGAAGPLGAIPSSHPQPANRLRLDQNQPRVVDASPGQRIRMTCRAEGFPPPAIEW---Q 1078

  Fly   207 LNGQP-SSVDNQ---NGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYSPIVSTHRHNV 267
            .:||| ||..:|   :|.:::..|..::.|.|.|:|.:|...... .|.:.|.....:|.....|
Human  1079 RDGQPVSSPRHQLQPDGSLVISRVAVEDGGFYTCVAFNGQDRDQR-WVQLRVLGELTISGLPPTV 1142

  Fly   268 NTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRT--TLIVREVTDSDLG 330
            ...:|.||.|.|....:.:...: .::|..:|...        |..|...  ||::..:...|.|
Human  1143 TVPEGDTARLLCVVAGESVNIRW-SRNGLPVQADG--------HRVHQSPDGTLLIYNLRARDEG 1198

  Fly   331 EYLC---QVENAIG-SNEVKVHVSYNPETPQFED 360
            .|.|   |...|:. |.|||| ||..| |.|..|
Human  1199 SYTCSAYQGSQAVSRSTEVKV-VSPAP-TAQPRD 1230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13506NP_001286718.1 IG_like 79..146 CDD:214653 19/67 (28%)
IGc2 83..146 CDD:197706 17/63 (27%)
IG_like 176..254 CDD:214653 22/116 (19%)
Ig 176..239 CDD:299845 19/101 (19%)
I-set 258..349 CDD:254352 24/96 (25%)
Ig 275..348 CDD:143165 19/78 (24%)
PAPLNNP_001352835.1 TSP1 29..80 CDD:214559
ADAM_spacer1 183..298 CDD:310520
TSP1 308..361 CDD:214559
TSP1 369..424 CDD:214559
TSP1 424..481 CDD:214559
TSP1 488..539 CDD:214559
Kunitz_BPTI 753..805 CDD:278443
Papilin_u7 814..905 CDD:318767 4/9 (44%)
Ig 914..>978 CDD:325142 19/70 (27%)
I-set 1049..1119 CDD:254352 18/72 (25%)
IG 1139..1219 CDD:214652 21/88 (24%)
PLAC 1235..1267 CDD:312271
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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