DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13506 and NTM

DIOPT Version :9

Sequence 1:NP_001286718.1 Gene:CG13506 / 37556 FlyBaseID:FBgn0034723 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:316 Identity:73/316 - (23%)
Similarity:116/316 - (36%) Gaps:48/316 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 VEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQNP--ISQRVQCMLNN----SILLRNVSP 137
            |..:.|:...|.|...|  ....|.|.....|:..|.:.  :..||..:.|.    ||.::||..
Human    45 VTVRQGESATLRCTIDN--RVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDV 107

  Fly   138 EDSDDYYCEIL----PQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPDNA 198
            .|...|.|.:.    |:..|.|..::|..::..:..|..|       .:|::..|.|........
Human   108 YDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISI-------NEGNNISLTCIATGRPEP 165

  Fly   199 TIKWSFNDLNGQPSSVD--NQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYSPIVS 261
            |:.|.    :..|.:|.  :::..:.:..:..:.:|||:|.|.:....|....|.:.|.|.|.:|
Human   166 TVTWR----HISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYIS 226

  Fly   262 THRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLIVREVTD 326
            ..: ......|....|.|...|.|.....:.||.|.| :..|..:|  |.|....:.||...|::
Human   227 EAK-GTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRL-IEGKKGVK--VENRPFLSKLIFFNVSE 287

  Fly   327 SDLGEYLCQVENAIGSNEVKVHVSYNPETPQFEDMTVEGNKVTLHWLVRSHQLLSE 382
            .|.|.|.|...|.:|.....:             |..|.|:.|      |..||.|
Human   288 HDYGNYTCVASNKLGHTNASI-------------MLFELNEPT------SSTLLQE 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13506NP_001286718.1 IG_like 79..146 CDD:214653 18/72 (25%)
IGc2 83..146 CDD:197706 17/68 (25%)
IG_like 176..254 CDD:214653 14/79 (18%)
Ig 176..239 CDD:299845 11/64 (17%)
I-set 258..349 CDD:254352 24/90 (27%)
Ig 275..348 CDD:143165 21/72 (29%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 22/88 (25%)
Ig strand A' 44..49 CDD:409353 1/3 (33%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 1/5 (20%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 2/11 (18%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 10/33 (30%)
Ig strand D 87..94 CDD:409353 2/6 (33%)
Ig strand E 97..103 CDD:409353 2/5 (40%)
Ig strand F 110..118 CDD:409353 2/7 (29%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 3/8 (38%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 136..205 CDD:404760 14/79 (18%)
Ig strand A' 142..147 CDD:409353 1/4 (25%)
Ig strand B 153..160 CDD:409353 2/6 (33%)
Ig strand C 166..171 CDD:409353 2/8 (25%)
Ig strand D 177..180 CDD:409353 1/2 (50%)
Ig strand E 184..190 CDD:409353 0/5 (0%)
Ig strand F 197..204 CDD:409353 4/6 (67%)
Ig strand G 211..219 CDD:409353 1/7 (14%)
Ig_3 222..299 CDD:404760 22/80 (28%)
putative Ig strand A 223..229 CDD:409353 2/5 (40%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143467
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.740

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