DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and opcml

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	285	Identity:	67/285 - (23%)
Similarity:	115/285 - (40%)	Gaps:	26/285 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 VEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQNPISQRVQCMLNN------SILLRNVSP 137
            :..:.||..:|.|...| ::|. |.|.....|:..|....|...:.:|.|      ||.:.||:.
Zfish    42 ITVRQGDSAVLKCSMDN-KVSR-VAWLNRTTILFTGNEKWSLDPRVVLLNTAVNEYSIKILNVNL 104

  Fly   138 EDSDDYYCEIL----PQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPDNA 198
            .|...|.|.||    |:..:.|..::|.||:..:..|..:       .:|.:..|.|........
Zfish   105 YDEGPYVCSILTNKKPESTKVHLIVQVPARIVNVSTDVSV-------NEGSNVSLMCLAIGRPEP 162

  Fly   199 TIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYSPIVSTH 263
            :|.|.|....|  :.:..:...:.:..:.:..:|.|.|:..:....|...||.:.|.|.|::|..
Zfish   163 SILWKFRSSKG--NRIVTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTVNYPPVISRA 225

  Fly   264 RHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLIVREVTDSD 328
            | :..|..|....|:|...|.|:....:.| |:...|:....:|  :.|...::.|....|::.|
Zfish   226 R-STGTAVGQKGVLWCEASAVPLADFQWFK-GERRILNGFNGVK--IENKGKQSMLTFFNVSEED 286

  Fly   329 LGEYLCQVENAIGSNEVKVHVSYNP 353
            .|.|.|...|.:|.....: :.|.|
Zfish   287 YGNYTCVAINTLGITNASI-ILYGP 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	19/72 (26%)
		IGc2	83..146	CDD:197706	19/68 (28%)
		IG_like	176..254	CDD:214653	13/77 (17%)
		Ig	176..239	CDD:299845	10/62 (16%)
		I-set	258..349	CDD:254352	22/90 (24%)
		Ig	275..348	CDD:143165	17/72 (24%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845	24/88 (27%)
		IG_like	41..129	CDD:214653	24/88 (27%)
		IG_like	139..216	CDD:214653	14/85 (16%)
		IGc2	146..202	CDD:197706	10/57 (18%)
		I-set	219..307	CDD:254352	22/92 (24%)
		ig	223..307	CDD:278476	21/88 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576341
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740