DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and Ama

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	64/301 - (21%)
Similarity:	131/301 - (43%)	Gaps:	42/301 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 VEAKPGDDVILNCDARNF-QLSNAVVWYK-------NRIIIANGQNPIS---QRVQCMLNN---- 128
            |.|..||.|..||..... |||  |.|.|       |.::::. :|.:|   ||....:..
  Fly    42 VVASVGDSVEFNCTVEEVGQLS--VSWAKRPSESDTNSVVLSM-RNILSLPDQRYNVTVTEGPKT 103

  Fly   129 -----SILLRNVSPEDSDDYYCEIL---PQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDH 185
                 :..::|:...|...|.|::|   .::|.:..:|::... .::.::   |.:|....:|.:
  Fly   104 GSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTP-PVIAEN---TPKSTLVTEGQN 164

  Fly   186 HKLECRTYLPDNATIKWSFNDLNGQPSSVDNQNGVIILD------NVDEKNAGDYQCLADDGSRH 244
            .:|.|........||.|:     .:.::|....|.::.:      :|...:.|.|.|:|.:|...
  Fly   165 LELTCHANGFPKPTISWA-----REHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQ 224

  Fly   245 PPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDS 309
            |....:.::|::.|.::..|..:......:|||.|:.:..|.....:.|:|..||.|..:.:.::
  Fly   225 PDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVANT 289

  Fly   310 VHNDHNRTTLI-VREVTDSDLGEYLCQVENAIGSNEVKVHV 349
            ..:....|::: :..|.:.|.|:|.|...|.:|..:.::|:
  Fly   290 ASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHL 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	21/86 (24%)
		IGc2	83..146	CDD:197706	19/82 (23%)
		IG_like	176..254	CDD:214653	16/83 (19%)
		Ig	176..239	CDD:299845	13/68 (19%)
		I-set	258..349	CDD:254352	20/91 (22%)
		Ig	275..348	CDD:143165	18/73 (25%)
Ama	NP_731114.2	I-set	33..143	CDD:254352	25/103 (24%)
		Ig	37..127	CDD:299845	22/87 (25%)
		IG_like	154..234	CDD:214653	16/84 (19%)
		IGc2	161..223	CDD:197706	14/66 (21%)
		I-set	254..330	CDD:254352	18/75 (24%)
		IGc2	254..322	CDD:197706	17/67 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740