DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13506 and wrapper

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	120/536 - (22%)
Similarity:	205/536 - (38%)	Gaps:	93/536 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RLLLISLLIGQLYVSCAGSPIDADVKGTDYQDDEYEYGDDTDDDDTQIIDVTKNHAEQEAPPYFD 73
            |.||.:|::||:..                   |.::.:|.::...                 |.
  Fly    10 RCLLAALILGQVQA-------------------ELDFNNDLENSQK-----------------FK 38

  Fly    74 VTDLRVEAKPGDDVILNCDARN-FQLSNAVVWYKNRIIIANGQN---PISQRVQCMLNNSILLRN 134
            .....|:....|.|.|.|.... |:.   |.|:::.:.:.:.::   |...|:....|.|:.:.|
  Fly    39 SIPTTVKTYENDTVQLPCTLNTPFRY---VRWHRDDVALVDSRHPELPPPDRIMLWPNGSLQVAN 100

  Fly   135 VSPEDSDDYYCEILPQR---VRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPD 196
            |...|:.|||||:....   |:|| |:.|.....:|.:..|:|::    |.|...::.|......
  Fly   101 VQSSDTGDYYCEMNSDSGHVVQQH-AIEVQLAPQVLIEPSDLTEQ----RIGAIFEVVCEAQGVP 160

  Fly   197 NATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHPPHGTVHIDVQYSPIVS 261
            ...|.|..|....||.|.......:||:......||..:|:|.:|...|....|::.|.:||.||
  Fly   161 QPVITWRLNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVS 225

  Fly   262 THRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQL-----SDKYSLKDSVHNDHN----RT 317
            ..:..|.|:.|:.|.|.|...|.|.....:...|..:.|     :.:..|:.:...||.    |.
  Fly   226 IPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRH 290

  Fly   318 TLIVREVTDSDLGEYLCQVENAIGSNEVKVHVSYNPETPQFE--DMTVEGNKVTLHWLVRSHQLL 380
            .|:|:.|.::|:|:|.|:..|.|......|.::..|....|:  ..|.......|.|...|...:
  Fly   291 MLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTSHVLVWQTESLLPI 355

  Fly   381 SEAMLDY----------QLTGSYTWSTVQVLETHRHNNTDNIWKIT-HQLELSRGVWHARVKTKN 434
            .|..|.:          |:..::|..|:....|   |....|...| |.|: ...::...|..:|
  Fly   356 MEFKLKFRQIPSNNVTRQVRTNWTELTIPAQAT---NGLIYITTYTLHGLQ-PASLYEVSVLARN 416

  Fly   435 TKGWS------HFSNDHVFEIPE---DSEVDKDEEVELPPDEIVQ-----AGIMPMSKGAASSMQ 485
            :.|||      .|:.....|:|.   :||:..|...|...:||.|     :..|..:.|:.:.
  Fly   417 SFGWSDNSKIVRFATGGEVELPNYSTESELQDDFTEEDFHNEITQRSEVLSASMMFNSGSVNG-- 479

  Fly   486 RLNVGVILLAALLLRV 501
            |..:...:.:..|:.:
  Fly   480 RGGISAFIYSLCLINI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	18/70 (26%)
		IGc2	83..146	CDD:197706	17/66 (26%)
		IG_like	176..254	CDD:214653	18/77 (23%)
		Ig	176..239	CDD:299845	14/62 (23%)
		I-set	258..349	CDD:254352	27/99 (27%)
		Ig	275..348	CDD:143165	20/81 (25%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	21/85 (25%)
		IG_like	41..118	CDD:214653	20/79 (25%)
		IG_like	145..218	CDD:214653	18/72 (25%)
		Ig	147..219	CDD:299845	17/71 (24%)
		I-set	224..323	CDD:254352	26/98 (27%)
		IGc2	236..314	CDD:197706	20/77 (26%)
		FN3	339..431	CDD:238020	20/95 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45080
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910