DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and DIP-zeta

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	91/466 - (19%)
Similarity:	173/466 - (37%)	Gaps:	86/466 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EAPPYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVW--YKNRIIIANGQNPISQRVQCMLNNS 129
            |.|.:.:..: .|....|.:|.|.|..:|.. |..|.|  ::...|:....:.|::..:..:.:.
  Fly   111 EEPEFTEYIE-NVTVPAGRNVKLGCSVKNLG-SYKVAWMHFEQSAILTVHNHVITRNPRISVTHD 173

  Fly   130 ---------ILLRNVSPEDSDDYYCEILPQRVR-QHTALRVGARLSILCDDRDITDRSQTFRQGD 184
                     :.:.||..||...|.|:|.....: |...|.|....:|   |..::......|:|.
  Fly   174 KHDRHRTWYLHINNVHEEDRGRYMCQINTVTAKTQFGYLNVVVPPNI---DDSLSSSDVIVREGA 235

  Fly   185 HHKLECRTYLPDNATIKWSFND-----LNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRH 244
            :..|.||........|||..:|     :|......:.:...:.:..:...:.|.|.|:|.:|...
  Fly   236 NISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRLDMGAYLCIASNGVPP 300

  Fly   245 PPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIK-DGKTLQLSDKYSLKD 308
            .....:.:.|.:.|::......|...:|....:.|...|.|...:|:.: :|..:..|.||.::.
  Fly   301 TVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRGEGPIIHDSHKYKVEA 365

  Fly   309 SV----HNDHNRTTLIVREVTDSDLGEYLCQVENAIGSNE--VKVHVSYNPETPQFEDMTVEGNK 367
            :|    :..|.:.|:|  .|:..|.|.|.|..:|..|..:  ::::|||.|.|..
  Fly   366 TVGLPAYKTHMKLTII--NVSSGDDGIYKCVAKNPRGETDGIIRLYVSYPPTTAS---------- 418

  Fly   368 VTLHWLVRSHQLLSEAMLDYQLTGSYT----WSTVQVLETHRHNNTDNIWKITHQLELSRGVWHA 428
                                  :|.|:    |....:...:.:...|:          :|.::
  Fly   419 ----------------------SGIYSTDTHWGENGINNNYAYGGPDS----------TRSIY-- 449

  Fly   429 RVKTKNTKGWSHFSNDHVFEIPEDSEVDKDEEVELPPDEIVQAGIMPMSKGAASSMQRLNVG--V 491
             .:.|||:..|:.:...:.|  :.|.:||.:...|......:|.  ..|.||......:.:.  .
  Fly   450 -AQDKNTRYQSNLNEIGLSE--QKSFLDKTQNPLLANGNANEAD--AESNGARGHNPSMAIAWLF 509

  Fly   492 ILLAALLLRVR 502
            :::|.|||.:|
  Fly   510 VVIATLLLTIR 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	16/77 (21%)
		IGc2	83..146	CDD:197706	15/73 (21%)
		IG_like	176..254	CDD:214653	15/82 (18%)
		Ig	176..239	CDD:299845	13/67 (19%)
		I-set	258..349	CDD:254352	22/97 (23%)
		Ig	275..348	CDD:143165	19/79 (24%)
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	21/97 (22%)
		Ig	130..200	CDD:143165	15/70 (21%)
		I-set	226..310	CDD:254352	15/83 (18%)
		IGc2	233..298	CDD:197706	13/64 (20%)
		Ig	313..410	CDD:299845	22/98 (22%)
		IG_like	325..410	CDD:214653	20/86 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740