DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and dpr4

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	78/392 - (19%)
Similarity:	125/392 - (31%)	Gaps:	133/392 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EAP---PYFDVTDLR-VEAKPGDDVILNCDARNFQLSNAVVWYKNR------IIIANGQNPISQR 121
            |.|   ||||.:..| |.|..|...:|:|..||.. ..||.|.:.|      :.|....|  .||
  Fly    39 ETPYSQPYFDNSSRREVTATVGQAALLHCRVRNLG-DRAVSWIRKRDLHILTVGILTYTN--DQR 100

  Fly   122 VQCMLNN-----SILLRNVSPEDSDDYYCEILPQ-RVRQHTALRVGARLSILCDDRDITDRSQTF 180
            .|.:.:.     ::.:.:..|.||..|.|::..: ::.|      |.||:::.....|...::.|
  Fly   101 FQSLHSEGSDEWTLRISSPQPRDSGTYECQVSTEPKISQ------GFRLNVVVSRAKILGNAELF 159

  Fly   181 RQGDHHKLECRTYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLADDGSRHP 245
                               || |.:|:|                         ..|||
  Fly   160 -------------------IK-SGSDIN-------------------------LTCLA------- 172

  Fly   246 PHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSV 310
                     ..||:                         |....|:.|..:.:..|.:..:....
  Fly   173 ---------MQSPV-------------------------PPSFIYWYKGKRVMNYSQRGGINVIT 203

  Fly   311 HNDHNRTTLIVREVTDSDLGEYLCQVENAIGSNEVKVHVSYNPETPQFEDMTVEGNKVTLHWLVR 375
            ......:.|::.:.|.:|.|.|.|...:: .|..|.||| .|.|.|.   ....||....  .:|
  Fly   204 ERSTRTSKLLIAKATPADSGNYTCSPSSS-DSASVVVHV-INGEHPA---AMQHGNSSAT--CLR 261

  Fly   376 SHQLLSEAMLDYQLTGSYTWSTVQVLETHRHNNTDNIWKITHQLELSRGVWHARVKTKNTKGWSH 440
            .   ||...:.:.|.   ||.::.|.....::|.:..|..:....     ||...|.    .||:
  Fly   262 P---LSSTSVPFVLA---TWMSMTVASVAWNSNLNINWNWSPDWR-----WHWNPKW----NWSN 311

  Fly   441 FS 442
            .:
  Fly   312 LA 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	20/77 (26%)
		IGc2	83..146	CDD:197706	18/73 (25%)
		IG_like	176..254	CDD:214653	9/77 (12%)
		Ig	176..239	CDD:299845	8/62 (13%)
		I-set	258..349	CDD:254352	14/90 (16%)
		Ig	275..348	CDD:143165	12/72 (17%)
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	26/101 (26%)
		IG_like	53..145	CDD:214653	26/100 (26%)
		ig	153..227	CDD:278476	20/159 (13%)
		IG_like	161..>227	CDD:214653	18/132 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900