DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and DIP-beta

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	80/335 - (23%)
Similarity:	132/335 - (39%)	Gaps:	54/335 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PYFDVTDLRVEAKPGDDVILNCDARNF---QLSN-------AVVWYK--NRIIIANGQNPI--SQ 120
            |.|.:....|....|.|....|...|.   ::|.       .|.|.|  .:.|:|..::.|  :.
  Fly    98 PDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNND 162

  Fly   121 RVQCMLNN----SILLRNVSPEDSDDYYCEILPQRVRQHTA-LRVGARLSILCDDRDITDRSQTF 180
            |:....|:    ::.:|.|..||:..|.|::....::..|| |.|.....|:.::   |......
  Fly   163 RLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIPPDIINEE---TSGDMMV 224

  Fly   181 RQGDHHKLECRTYLPDNATIKWSFND------LNG-----QPSSVDNQNGVIILDNVDEKNAGDY 234
            .:|...||.||........|.|...|      .||     :..||:.:  ::.|..:.....|.|
  Fly   225 PEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGE--MLTLSKITRSEMGAY 287

  Fly   235 QCLADDGSRHPPHGTV----HIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKD- 294
            .|:|.:|.  ||  ||    .:.|.:.|:|......|.........|.||..|.|...:|:.::
  Fly   288 MCIASNGV--PP--TVSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQREN 348

  Fly   295 GKTLQLSDKYSLKDSVHNDHN-RTTLIVREVTDSDLGEYLCQVENAIGSNEVKVHVSYNPETPQF 358
            |:.:...|:|:|.:..:|.:. ...|.::.:..||.|.|.|..:|:||..|..:.: |..|.|
  Fly   349 GEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRL-YEMERP-- 410

  Fly   359 EDMTVEGNKV 368
                  |.|:
  Fly   411 ------GKKI 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	19/84 (23%)
		IGc2	83..146	CDD:197706	18/80 (23%)
		IG_like	176..254	CDD:214653	22/92 (24%)
		Ig	176..239	CDD:299845	16/73 (22%)
		I-set	258..349	CDD:254352	24/92 (26%)
		Ig	275..348	CDD:143165	21/74 (28%)
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	26/110 (24%)
		ig	102..195	CDD:278476	20/92 (22%)
		IG_like	219..307	CDD:214653	22/93 (24%)
		Ig	221..307	CDD:299845	22/91 (24%)
		Ig	311..404	CDD:299845	24/92 (26%)
		IG_like	327..405	CDD:214653	21/78 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740