DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and ncam1a

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_009293555.1	Gene:	ncam1a / 30447	ZFINID:	ZDB-GENE-990415-31	Length:	1010	Species:	Danio rerio

Alignment Length:	419	Identity:	91/419 - (21%)
Similarity:	159/419 - (37%)	Gaps:	97/419 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 DTDDDDTQIIDVTKNHAEQEAP-PYFDVTDLRVEAKPGDDVILNCDARNFQLSN---AVVW-YKN 107
            :.:...|.|:.:.:....|.|| |.        |...|||..:.||.    :|:   .::| ||.
Zfish   100 EKESQGTIIVKIFQKLTFQYAPSPQ--------EFNEGDDADIICDV----ISSPPPTIIWRYKK 152

  Fly   108 RIIIANGQNPISQRVQCMLNNSILLRNVSPEDSDDYYCE-------------------ILPQRVR 153
            ..|    |.....|::.:.||.:.:|.:...|..||.||                   :||....
Zfish   153 MRI----QPETDVRLKVLSNNHLQIRGIKKTDEGDYTCEGRIMARGEIDLRVIKVIVNVLPSIRT 213

  Fly   154 QHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPDNATIKWSFNDL---NGQPSSVD 215
            ::|.|...|.:     ::.:|             |.|........|:||:..:.   :.:..|::
Zfish   214 RYTELNATADI-----NQAVT-------------LACHADGYPEPTVKWARGNTELESDEKYSLN 260

  Fly   216 NQNGVIILDNVDEKNAGDYQCLADD--GSRHPPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELY 278
            .....:.:.:|::.:.|||:|:|.:  |.|..   .|.::|...|.::...:...:|......|.
Zfish   261 EDGSELTIKDVNKLDEGDYKCIARNKAGERSE---EVTLNVFVQPKITFLENQTASELEEQITLT 322

  Fly   279 CNYRAKP-------IGRSYFIKDGK-TLQLSDKYSLKDS---VHNDHNRTTLIVREVTDSDLGEY 332
            |.....|       .||..|.::.: :....:|:...|.   |.:|...::|.::.|..:|.|:|
Zfish   323 CEATGDPTPNIIWSFGRRVFTENEQASWTRPEKHKSLDGNVVVRSDARVSSLTLKYVQFTDAGQY 387

  Fly   333 LCQVENAIGSN--EVKVHVSYNP--ETPQFEDMTVEGNKVTL------H------WLVRSHQLLS 381
            ||...|:||.:  .:.:.|.|.|  :.|| ...|.|||...:      |      |.....||.|
Zfish   388 LCTARNSIGQDIQSMYLEVRYAPKIQGPQ-AVFTWEGNPANITCEALAHPGASVLWFRDGQQLPS 451

  Fly   382 EAMLDYQLTGSYTWSTVQVLETHRHNNTD 410
            ....:.::   |...||..||....:..|
Zfish   452 ANTTNVKI---YNTPTVSFLEVTPDSQND 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	19/70 (27%)
		IGc2	83..146	CDD:197706	18/66 (27%)
		IG_like	176..254	CDD:214653	15/82 (18%)
		Ig	176..239	CDD:299845	11/65 (17%)
		I-set	258..349	CDD:254352	22/103 (21%)
		Ig	275..348	CDD:143165	20/85 (24%)
ncam1a	XP_009293555.1	Ig	20..112	CDD:299845	2/11 (18%)
		I-set	21..111	CDD:254352	2/10 (20%)
		IG_like	121..200	CDD:214653	23/94 (24%)
		IGc2	128..189	CDD:197706	20/68 (29%)
		Ig	208..301	CDD:299845	22/113 (19%)
		IG_like	219..298	CDD:214653	17/99 (17%)
		Ig	300..406	CDD:299845	22/105 (21%)
		IG_like	308..406	CDD:214653	21/97 (22%)
		ig	413..498	CDD:278476	17/69 (25%)
		IG_like	415..498	CDD:214653	17/67 (25%)
		fn3	505..589	CDD:278470
		FN3	624..715	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900