DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and Il18r1

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_001100375.1	Gene:	Il18r1 / 301365	RGDID:	1308589	Length:	537	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	66/329 - (20%)
Similarity:	124/329 - (37%)	Gaps:	77/329 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 EAPPYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQNPISQRVQCML---NN 128
            |..|::        .||.|   ::....|.:.: .:.|:|..  .::|...::.|....:   .:
  Rat    32 EGEPFY--------LKPCD---MSAPMHNNETA-TMRWFKGN--ASHGYRELNMRSSPRIAFHGH 82

  Fly   129 SILLRNVSPEDSDDYYCEILPQRVRQHTALRVGARLSILC-DDRDITDRSQTFRQGDHHKLECRT 192
            ::....|..||...|:.::  ...||:..|.|..|....| .::.:|:|....::......|..:
  Rat    83 ALEFWPVELEDKGTYFSQV--GNDRQNWTLNVTKRNKHSCFSEKLVTNRDVEVKKSLWITCENPS 145

  Fly   193 Y--LPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLAD---DGSRHPPHGTVHI 252
            |  |.::..:..:..:::..|         :||.:.:..:.|.|.|:..   :|.::....||:|
  Rat   146 YGELINHTLLYKNCKEISKTP---------MILKDAEFGDEGYYSCVFSVHHNGQQYNITKTVNI 201

  Fly   253 DV-----QYSP-IVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKY------- 304
            .|     :.:| |..:....|..|.|...||.|:               ..|..:|.:
  Rat   202 TVIEGNSKITPAIFGSKSAKVGVELGEDVELNCS---------------AVLNRNDLFYWSIRKE 251

  Fly   305 -SLKDSVHNDHNRTT------------LIVREVTDSDLGE-YLCQVENAIGSNEVKVHVSYNPET 355
             ||..:||.|.|.||            |.:::||:..|.. |.|.|.|. .:.:.|..:....||
  Rat   252 DSLDPNVHEDRNETTWTFEGKLHASKILRIQKVTEKYLNVLYNCTVANE-EATDTKSFILVRKET 315

  Fly   356 PQFE 359
            |..:
  Rat   316 PDIQ 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	12/69 (17%)
		IGc2	83..146	CDD:197706	11/65 (17%)
		IG_like	176..254	CDD:214653	14/82 (17%)
		Ig	176..239	CDD:299845	10/64 (16%)
		I-set	258..349	CDD:254352	27/112 (24%)
		Ig	275..348	CDD:143165	22/93 (24%)
Il18r1	NP_001100375.1	Ig_2	22..112	CDD:290606	17/95 (18%)
		Ig	<156..205	CDD:299845	11/57 (19%)
		IG_like	224..310	CDD:214653	24/101 (24%)
		TIR	370..519	CDD:214587
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000