Protein Alignment CG13506 and IL1RAPL2

DIOPT Version :9

• Sequence 1: NP_001286718.1
• Gene: CG13506 / 37556
• FlyBaseID: FBgn0034723
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_059112.1
• Gene: IL1RAPL2 / 26280
• HGNCID: 5997
• Length: 686
• Species: Homo sapiens
• Alignment Length: 562
• Identity: 98/562 - (17%)
• Similarity: 161/562 - (28%)
• Gaps: 239/562 - (42%)

  Fly    81 AKPGDDVILNCD------ARNFQLSNA----VVWYKNRIIIANGQNPI--SQRVQCMLNNSILLR 133
            |..|:.|.:.|.      ..|:..:.:    ::||||:   .:.:.||  |:.......:||...
Human    43 ALAGEPVRVKCALFYSYIRTNYSTAQSTGLRLMWYKNK---GDLEEPIIFSEVRMSKEEDSIWFH 104

  Fly   134 NVSPEDSDDYYCEI-----------------------LPQRVRQHTALRVGARLSILCDDRDITD 175
            :...:||..|.|.:                       ...|:|......|..|..|.|.|.|
Human   105 SAEAQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMD--- 166

  Fly   176 RSQTFRQGDHHK-----LECRTYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQ 235
               .|::.|...     .||:..:       |.        |.:..:...:::..|.|::.|:|.
Human   167 ---DFKKSDQEPDVVWYKECKPKM-------WR--------SIIIQKGNALLIQEVQEEDGGNYT 213

  Fly   236 C-LADDG---------------SRHPPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAK 284
            | |..:|               :..||.....::.|.|.|        :.:.|....:.|.....
Human   214 CELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVI--------DVQLGKPLNIPCKAFFG 270

  Fly   285 PIGRS----YFIKDGKTLQ-------LSDKYSLKDSVHNDHNRTTLIVREVTDSDLGEYLCQVEN 338
            ..|.|    |::|..|.::       ..:...||:.:........||...|.::||..|.|.|||
Human   271 FSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELALIFDSVVEADLANYTCHVEN 335

  Fly   339 AIG------------------------------------------------------------SN 343
            ..|                                                            :.
Human   336 RNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLVLLVVIYKCYNIELMLFYRQHFGADETNDDNK 400

  Fly   344 EVKVHVSY-----------NPETPQF-------------------------------EDMTVEGN 366
            |...::||           |||..||                               ||:|
Human   401 EYDAYLSYTKVDQDTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLT---- 461

  Fly   367 KVTLHWLVRSHQLLSEAMLDYQLTGSYTWSTVQVLETHRHN---------------------NTD 410
                .::.:|.:|:.....||.|...  ||..: ||:..||                     |..
Human   462 ----RYVEQSRRLIIVLTPDYILRRG--WSIFE-LESRLHNMLVSGEIKVILIECTELKGKVNCQ 519

  Fly   411 NIWKITHQLE-LSRGVWHARVKTK-NTKGWSHFSNDHVFEIP 450
            .:..:...:: ||...|.....:| |:|.|.|.    |:|:|
Human   520 EVESLKRSIKLLSLIKWKGSKSSKLNSKFWKHL----VYEMP 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	17/76 (22%)
		IGc2	83..146	CDD:197706	16/74 (22%)
		IG_like	176..254	CDD:214653	15/98 (15%)
		Ig	176..239	CDD:299845	12/68 (18%)
		I-set	258..349	CDD:254352	22/161 (14%)
		Ig	275..348	CDD:143165	20/143 (14%)
IL1RAPL2	NP_059112.1	Ig	32..133	CDD:325142	18/92 (20%)
		Ig2_IL1R_like	146..237	CDD:319309	20/111 (18%)
		IG_like	250..347	CDD:214653	22/104 (21%)
		TIR	402..563	CDD:307630	33/171 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000