DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13506 and LRIT1

DIOPT Version :9

Sequence 1:NP_001286718.1 Gene:CG13506 / 37556 FlyBaseID:FBgn0034723 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:299 Identity:65/299 - (21%)
Similarity:107/299 - (35%) Gaps:99/299 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   272 GATAELYCNYRAKPIG--RSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLI-VREVTDSDLGEYL 333
            |.||.|.|.....| |  .|:...:|:.|    ..::...|.:|....||: :..|:..|.|:|:
Human   268 GGTALLRCGATGVP-GPEMSWRRANGRPL----NGTVHQEVSSDGTSWTLLGLPAVSHLDSGDYI 327

  Fly   334 CQVENAIGSNE--VKVHVSYNPETPQFE--------------DMTVEGNKVTLHWLVRSH--QLL 380
            ||.:|.:|::|  :.:.|:..|.:.:..              :.....||     ||..|  |:.
Human   328 CQAKNFLGASETVISLIVTEPPTSTEHSGSPGALWARTGGGGEAAAYNNK-----LVARHVPQIP 387

  Fly   381 SEAMLDYQLTGSYTWSTVQVLETHRHNNTDNIWKIT----------------------HQLELSR 423
            ..|:|   .||....||.:.| |..|...|.:.:::                      |.:.|  
Human   388 KPAVL---ATGPSVPSTKEEL-TLEHFQMDALGELSDGRAGPSEARMVRSVKVVGDTYHSVSL-- 446

  Fly   424 GVWHARVKTKNTKGWS-------HFSNDHVFEIPEDSEVD----------------------KDE 459
             ||.| .:.|||..:|       ..|...|...|..:.|.                      |::
Human   447 -VWKA-PQAKNTTAFSVLYAVFGQHSMRRVIVQPGKTRVTITGLLPKTKYVACVCVQGLVPRKEQ 509

  Fly   460 EVELPPDEIVQAGIMPMSKGAASSMQRLNVGVILLAALL 498
            .|....:|:|.         |.::.|.:||.||.:|.::
Human   510 CVIFSTNEVVD---------AENTQQLINVVVISVAIVI 539

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13506NP_001286718.1 IG_like 79..146 CDD:214653
IGc2 83..146 CDD:197706
IG_like 176..254 CDD:214653
Ig 176..239 CDD:299845
I-set 258..349 CDD:254352 23/81 (28%)
Ig 275..348 CDD:143165 21/77 (27%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 23/81 (28%)
IG_like 267..345 CDD:214653 23/81 (28%)
FN3 431..498 CDD:214495 13/70 (19%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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