DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and Il1r1

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_037255.3	Gene:	Il1r1 / 25663	RGDID:	2892	Length:	590	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	74/317 - (23%)
Similarity:	126/317 - (39%)	Gaps:	57/317 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 DARNFQLS------NAVVWYKNRIIIANGQNPIS----QRVQCMLNNSILLRNVSPEDSDDYYCE 146
            |.|:..|:      ..::||||     :.:.|||    .|:. ..|..:.......|||..|||
  Rat    56 DIRSCPLTPNEMHGGTIIWYKN-----DSKTPISADKDSRIH-QQNEHLWFVPAKMEDSGYYYC- 113

  Fly   147 ILPQRVRQHT-ALRVGARLSILCDDRDITDRSQ-TFRQGDHHKLECRTYLPDNATIKWSFNDL-- 207
                .:|..| .|:....:|:|.:|..:...:| :|.|..|...:.....|.....|...|:|
  Rat   114 ----IMRNSTYCLKTKITMSVLENDPGLCYNTQASFIQRLHVAGDGSLVCPYLDFFKDENNELPK 174

  Fly   208 -----NGQPSSVDNQN-----GVIILDNVDEKNAGDYQCLAD---DGSRHPPHGTV-HIDVQYS- 257
                 |.:|..:|:.|     ..:::.||.|::.|:|.|...   .|.::|....: .|.:..|
  Rat   175 VQWYKNCKPLPLDDGNFFGFKNKLMVMNVAEEHRGNYTCRTSYTYQGKQYPVTRVITFITIDDSK 239

  Fly   258 ---PIVSTHRH-NVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNR-- 316
               |::.:.|: .:..:.|:|.:|.||...:.....|:..:|..::..|....:|....:|..
  Rat   240 RDRPVIMSPRNETMEADPGSTIQLICNVTGQFTDLVYWKWNGSEIEWDDPILAEDYQFLEHPSAK 304

  Fly   317 ------TTLIVREVTDSDLGEY--LCQVENAIGSNEVKVHVSYNPETPQFEDMTVEG 365
                  |||.|.|| .|....|  :|.|:|........|.:.|  ..|.|::..:.|
  Rat   305 RKYTLITTLNVSEV-KSQFYRYPFICFVKNTHILETAHVRLVY--PVPDFKNYLIGG 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	17/63 (27%)
		IGc2	83..146	CDD:197706	17/63 (27%)
		IG_like	176..254	CDD:214653	21/94 (22%)
		Ig	176..239	CDD:299845	18/75 (24%)
		I-set	258..349	CDD:254352	24/101 (24%)
		Ig	275..348	CDD:143165	19/82 (23%)
Il1r1	NP_037255.3	Ig	47..130	CDD:299845	21/84 (25%)
		Ig2_IL1R_like	144..236	CDD:143234	20/91 (22%)
		Ig_3	242..333	CDD:290638	22/91 (24%)
		IG_like	251..344	CDD:214653	22/93 (24%)
		TIR	401..556	CDD:214587
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000