DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and zig-3

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	51/221 - (23%)
Similarity:	76/221 - (34%)	Gaps:	72/221 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 TFRQGDHHKLECRTYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEK--NA---------- 231
            |...|:...|.|.........|.|   :.:||....|.:.      ||.||  ||
Worm    54 TVSTGESVTLRCDVLSTPTGVIYW---EKDGQRIQGDKEL------NVFEKVLNAMGPTVESGII 109

  Fly   232 --------------GDYQCLADDGSRHPPHGTVH------IDVQYSPIVSTHRH----NVNTE-- 270
                          |.|:|:|.:|     |.||.      ::.|.....||.|.    .::||
Worm   110 TSSYQIPCANLHHIGSYKCVATNG-----HDTVESSAKISVEGQTVKCKSTRRSAPVITMSTESR 169

  Fly   271 ---KGATAELYCNYRA-KPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTTLIVREVTDSDLGE 331
               :...|.|.|  || :....::..:|.|....|.:|.|..|       ..|::|::..||:|.
Worm   170 FELQDNAATLIC--RADRRANWNWMFEDKKIDFDSGRYELLPS-------GDLLIRKIQWSDMGS 225

  Fly   332 YLCQVENAIGSNE-------VKVHVS 350
            |.|...|..|.:.       .|.|::
Worm   226 YFCIAHNKYGESRGETFLYPTKKHIA 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653
		IGc2	83..146	CDD:197706
		IG_like	176..254	CDD:214653	23/106 (22%)
		Ig	176..239	CDD:299845	18/85 (21%)
		I-set	258..349	CDD:254352	26/107 (24%)
		Ig	275..348	CDD:143165	21/80 (26%)
zig-3	NP_509336.1	I-set	45..145	CDD:254352	23/104 (22%)
		Ig	61..142	CDD:143165	21/94 (22%)
		IG_like	177..244	CDD:214653	20/75 (27%)
		Ig	<191..237	CDD:299845	15/52 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900