Protein Alignment CG13506 and wrk-1

DIOPT Version :10

• Sequence 1: NP_611666.2
• Gene: CG13506 / 37556
• FlyBaseID: FBgn0034723
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_001024651.1
• Gene: wrk-1 / 181093
• WormBaseID: WBGene00006942
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 101/439 - (23%)
• Similarity: 181/439 - (41%)
• Gaps: 99/439 - (22%)

  Fly    81 AKPGDDVILNCDARNFQLSNAVVWYKNRIIIA--------NGQNPISQRVQCMLNNSIL-LRNVS 136
            ||.|:.:.|.|:..:  .|.|::|.||..::|        .|...||...    :.|:| ::.|.
 Worm    29 AKEGESLTLRCEVED--PSVAIIWRKNTEVVAVDDEILDTYGGYEISMEG----STSVLTIKRVE 87

  Fly   137 PEDSDDYYCEILPQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLECRTYLPD----- 196
            |.:|.:|.|.:....|.....::|                 |.|:.............||
 Worm    88 PINSANYSCALAEPEVSVTFVIKV-----------------QVFKPTQVSVKPLVVISPDTGVYH 135

  Fly   197 ------NATIKWSFNDLNGQPSSV--------------DNQNGVIILDNVDEKNAGDYQCLADD- 240
                  |..|.....:.|.:|..|              ::....|::..|.:.:||.|.|||::
 Worm   136 ARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPEDIKREHGGARIVITEVKKHHAGKYNCLAENI 200

  Fly   241 -GSRHPPHGTVHIDV--------QYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGK 296
             ||   ...|:.|.|        :..|.|......:...|...|..:|.|...|:.:..::.:|.
 Worm   201 AGS---DRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGY 262

  Fly   297 TLQLSDKYSLKDSVH----NDHNRTTLIVREVTDSDLGEYLCQVENAIGSNEVKVHVSYNPETPQ 357
            .:..:|:...|.|..    |.::::||.|.::::...|:|.|::.|.:||....||||..|..||
 Worm   263 KINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTAVVHVSGRPGPPQ 327

  Fly   358 FEDMTVEGNKVTLHWLVRSHQLLSEAMLDYQLTGSYTW-----STVQVLETHRHNNTDNIWKITH 417
               ::.:.:::|  |.||:...:.|..|.::|..:..:     ::|:|.::  .||.|:.|  ||
 Worm   328 ---LSFDESELT--WTVRAFDKILEYQLCHRLENADHFLPEDCNSVRVKKS--DNNGDDKW--TH 383

  Fly   418 QLELSR-----GVWHARVKTKNTKGWSHFSND--HVFEIPEDSEVDKDE 459
            .::||.     ..:|.::|.:|..||...:.|  ||    |...::|:|
 Worm   384 TIDLSTFLEHGNKYHVQLKARNALGWGSMAKDALHV----ELQRIEKEE 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_611666.2	Ig_3	69..146	CDD:464046	20/73 (27%)
		Ig_3	173..238	CDD:464046	15/89 (17%)
		Ig	258..349	CDD:472250	22/94 (23%)
		Ig strand B	275..279	CDD:409353	1/3 (33%)
		Ig strand C	288..292	CDD:409353	0/3 (0%)
		Ig strand E	317..321	CDD:409353	2/3 (67%)
		Ig strand F	331..336	CDD:409353	2/4 (50%)
wrk-1	NP_001024651.1	IG_like	25..113	CDD:214653	23/106 (22%)
		Ig strand B	35..39	CDD:409353	1/3 (33%)
		Ig strand C	47..51	CDD:409353	1/3 (33%)
		Ig strand E	77..83	CDD:409353	2/5 (40%)
		Ig strand F	93..98	CDD:409353	2/4 (50%)
		Ig strand G	104..107	CDD:409353	0/2 (0%)
		Ig	136..212	CDD:472250	17/78 (22%)
		Ig strand B	143..147	CDD:409353	1/3 (33%)
		Ig strand C	157..161	CDD:409353	1/3 (33%)
		Ig strand E	178..182	CDD:409353	1/3 (33%)
		Ig strand F	192..197	CDD:409353	2/4 (50%)
		Ig	235..319	CDD:472250	20/83 (24%)
		Ig strand C	254..258	CDD:409353	0/3 (0%)
		Ig strand E	278..291	CDD:409353	3/12 (25%)
		Ig strand F	301..306	CDD:409353	2/4 (50%)
		Ig strand G	314..317	CDD:409353	0/2 (0%)