DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and Kirrel

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	484	Identity:	96/484 - (19%)
Similarity:	174/484 - (35%)	Gaps:	142/484 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 PPYFDVTDLRVEAKP------GDDVILNCDARNFQLSNAVVWYKNRI----------IIANG--Q 115
            ||    .:.|::..|      |....|.|.|.|.:.:..::|:::..          ::.:|  :
Mouse   151 PP----EETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRE 211

  Fly   116 NPISQRVQCMLNNSILLRNVSPEDSD---DYYCEILPQRVRQHTALRVGARLSILCDDR-----D 172
            ..|||.:            :.|.|.|   .:.|..:      :.|:..|...||..|..     .
Mouse   212 TTISQLL------------IEPTDLDIGRVFTCRSM------NEAIPNGKETSIELDVHHPPTVT 258

  Fly   173 ITDRSQTFRQGDHHKLECR-TYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVD---EKNAGD 233
            ::...||..:|:.....|: |..|:....:|:             :.|.:|.|..:   |.|. |
Mouse   259 LSIEPQTVLEGERVIFTCQATANPEILGYRWA-------------KGGFLIEDAHESRYETNV-D 309

  Fly   234 YQCLADD---------GSRHPPHGTVHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAK-PIGR 288
            |....:.         ||.:.   :..::|.::|.:..:.....|:.|:...|.|.:... |:..
Mouse   310 YSFFTEPVSCEVYNKVGSTNV---STLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTL 371

  Fly   289 SYFIKD---GKTLQLS-DKYSLKDSVHNDHNRTTLIVREVTDSDLGEYLCQV---ENAIGSNEVK 346
            ::..||   |..|..| .:.:|...|.::.|:  |:::.||.:|.|.|.|:.   ...:...||.
Mouse   372 TWTKKDSNMGPRLPGSPPEANLSAQVLSNSNQ--LLLKSVTQADAGTYTCRAIVPRIGVAEREVP 434

  Fly   347 VHVSYNP----ETPQFEDMTVEGNKV-----------TLHWLVRSHQL----LSEAMLDYQLTGS 392
            ::|:..|    |..||. :..:|.||           .:.|..:.:.|    |....::...:||
Mouse   435 LYVNGPPIISSEAVQFA-VRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGS 498

  Fly   393 YTWSTVQVLETHRHNNTDNIWKITHQLELSRGVWHARVKTK-NTKGWSHFSNDHVFEIPEDSEVD 456
            ...||:.:      ||                |..|..:|. |...|:.|.       |..:.:.
Mouse   499 GVLSTLTI------NN----------------VMEADFQTHYNCTAWNSFG-------PGTAIIQ 534

  Fly   457 KDEEVELPPDEI----VQAGIMPMSKGAA 481
            .:|...||...|    :.|||:.:...||
Mouse   535 LEEREVLPVGIIAGATIGAGILVVFSFAA 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	14/87 (16%)
		IGc2	83..146	CDD:197706	14/83 (17%)
		IG_like	176..254	CDD:214653	16/90 (18%)
		Ig	176..239	CDD:299845	14/66 (21%)
		I-set	258..349	CDD:254352	23/98 (23%)
		Ig	275..348	CDD:143165	20/80 (25%)
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229
		Ig2_KIRREL3-like	170..251	CDD:143236	17/98 (17%)
		Ig	255..336	CDD:386229	16/97 (16%)
		Ig_3	340..421	CDD:372822	21/82 (26%)
		Ig5_KIRREL3	439..536	CDD:143306	23/126 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900