DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13506 and Il18r1

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_032391.1	Gene:	Il18r1 / 16182	MGIID:	105383	Length:	537	Species:	Mus musculus

Alignment Length:	272	Identity:	59/272 - (21%)
Similarity:	94/272 - (34%)	Gaps:	65/272 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 VSPEDSDDYYCEILPQRVRQHTALRVGARLSILC-DDRDITDRSQTFRQGDHHKLECR------- 191
            |..||...|..::  ...|::..|.|..|....| .|:.:|.|.....:..|  :.|:
Mouse    89 VEMEDEGTYISQV--GNDRRNWTLNVTKRNKHSCFSDKLVTSRDVEVNKSLH--ITCKNPNYEEL 149

  Fly   192 ---TYLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVDEKNAGDYQCLAD---DGSRHPPHGTV 250
               |:|..|.      .:::..|.         ||.:.:..:.|.|.|:..   :|:|:....||
Mouse   150 IQDTWLYKNC------KEISKTPR---------ILKDAEFGDEGYYSCVFSVHHNGTRYNITKTV 199

  Fly   251 HIDV-----QYSP-IVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDS 309
            :|.|     :.:| |:......|..|.|...||.|:.........|:     :::..|  |...:
Mouse   200 NITVIEGRSKVTPAILGPKCEKVGVELGKDVELNCSASLNKDDLFYW-----SIRKED--SSDPN 257

  Fly   310 VHNDHNRTTLIVRE-------------VTDSDLGE-YLCQV--ENAIGSNEVKVHVSYNPETPQF 358
            |..|...||..:.|             :|::.|.. |.|.|  |.||   :.|..|....|.|..
Mouse   258 VQEDRKETTTWISEGKLHASKILRFQKITENYLNVLYNCTVANEEAI---DTKSFVLVRKEIPDI 319

  Fly   359 EDMTVEGNKVTL 370
            ......|....|
Mouse   320 PGHVFTGGVTVL 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	4/10 (40%)
		IGc2	83..146	CDD:197706	4/10 (40%)
		IG_like	176..254	CDD:214653	17/90 (19%)
		Ig	176..239	CDD:299845	12/72 (17%)
		I-set	258..349	CDD:254352	25/107 (23%)
		Ig	275..348	CDD:143165	20/88 (23%)
Il18r1	NP_032391.1	IG_like	26..112	CDD:214653	6/24 (25%)
		Ig	131..205	CDD:386229	17/90 (19%)
		PHA02785	<157..257	CDD:165149	24/121 (20%)
		TIR	374..534	CDD:366714
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000