DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13506 and Il1rap

DIOPT Version :9

Sequence 1:NP_001286718.1 Gene:CG13506 / 37556 FlyBaseID:FBgn0034723 Length:503 Species:Drosophila melanogaster
Sequence 2:NP_001152790.1 Gene:Il1rap / 16180 MGIID:104975 Length:685 Species:Mus musculus


Alignment Length:523 Identity:107/523 - (20%)
Similarity:178/523 - (34%) Gaps:161/523 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 EYEYGDDTDDDDTQIIDVTKNHAEQEAPPYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVWYK 106
            :|.|........|.|...|:...:.|.|..|.:.:.|: :|..|                |:|::
Mouse    55 KYNYSTAHSSGLTLIWYWTRQDRDLEEPINFRLPENRI-SKEKD----------------VLWFR 102

  Fly   107 NRIIIANGQNPISQRVQCMLNNSILLRNVSPEDSDDYYCEILPQRVRQHTALRVGARLSILCDDR 171
            ..::...|      ...|||.|:.....|:      :..|::.:....::|:|.......:    
Mouse   103 PTLLNDTG------NYTCMLRNTTYCSKVA------FPLEVVQKDSCFNSAMRFPVHKMYI---- 151

  Fly   172 DITDRSQTFRQGDH--HKLECRT---YLPDNATIKWSFNDLNGQPSSVDNQNGVIILDNVD---- 227
                        :|  ||:.|..   |.|  :::|.|.....|....||..|  ::.:.::    
Mouse   152 ------------EHGIHKITCPNVDGYFP--SSVKPSVTWYKGCTEIVDFHN--VLPEGMNLSFF 200

  Fly   228 ---EKNAGDYQCLADDGSRHPPHG-------TVHIDVQYS------PIVSTHRHNVNTEKGATAE 276
               ..|.|:|.|:.    .:|.:|       ||.:.|..|      |.:.:....|..||....|
Mouse   201 IPLVSNNGNYTCVV----TYPENGRLFHLTRTVTVKVVGSPKDALPPQIYSPNDRVVYEKEPGEE 261

  Fly   277 L------YCNYRAKPIGRSYFIKDGK-----TLQLSDKYSLKDSVHNDHNRTTLI-VREVTDSDL 329
            |      |.::........::..|||     |:.::...|:..|...|..||.:: :::||..||
Mouse   262 LVIPCKVYFSFIMDSHNEVWWTIDGKKPDDVTVDITINESVSYSSTEDETRTQILSIKKVTPEDL 326

  Fly   330 -GEYLCQVENAIGSNEVKVHVSYNPETPQFEDMTVE-----GNKVTL----------HWL----- 373
             ..|:|...|..|..|....|......|::   |||     |..|.|          :||     
Mouse   327 RRNYVCHARNTKGEAEQAAKVKQKVIPPRY---TVELACGFGATVFLVVVLIVVYHVYWLEMVLF 388

  Fly   374 VRSHQLLSEAMLD---YQLTGSYTWSTVQVLETHRHNNTDNIWKITHQLELSRGVWHARVKTKNT 435
            .|:|....|.:||   |.:..||               ..|:.:....|...|||      .:|.
Mouse   389 YRAHFGTDETILDGKEYDIYVSY---------------ARNVEEEEFVLLTLRGV------LENE 432

  Fly   436 KGWS--HFSNDHVFEIPEDSEVD---------KDEEVELPPDEIVQAGIMPMSKGAASSMQRLNV 489
            .|:.  .|..|   .:|..:.|:         :...|.|.||.:.:..|         ||....:
Mouse   433 FGYKLCIFDRD---SLPGGNTVEAVFDFIQRSRRMIVVLSPDYVTEKSI---------SMLEFKL 485

  Fly   490 GVI 492
            ||:
Mouse   486 GVM 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13506NP_001286718.1 IG_like 79..146 CDD:214653 10/66 (15%)
IGc2 83..146 CDD:197706 9/62 (15%)
IG_like 176..254 CDD:214653 20/96 (21%)
Ig 176..239 CDD:299845 16/74 (22%)
I-set 258..349 CDD:254352 25/103 (24%)
Ig 275..348 CDD:143165 21/85 (25%)
Il1rapNP_001152790.1 Ig1_IL1R_like 25..132 CDD:409584 20/105 (19%)
Ig strand B 43..47 CDD:409584
Ig strand C 67..71 CDD:409584 2/3 (67%)
Ig strand E 97..101 CDD:409584 2/19 (11%)
Ig strand F 111..116 CDD:409584 1/4 (25%)
Ig strand G 124..127 CDD:409584 1/8 (13%)
Ig 145..235 CDD:416386 21/113 (19%)
Ig strand A 145..150 CDD:409353 0/4 (0%)
Ig strand A 145..150 CDD:409353 0/4 (0%)
Ig strand B 156..160 CDD:409353 2/3 (67%)
Ig strand B 156..160 CDD:409353 2/3 (67%)
Ig strand C 174..179 CDD:409353 1/4 (25%)
Ig strand C 174..179 CDD:409353 1/4 (25%)
Ig strand C' 182..184 CDD:409353 0/1 (0%)
Ig strand C' 182..184 CDD:409353 0/1 (0%)
Ig strand D 189..193 CDD:409353 1/5 (20%)
Ig strand D 189..193 CDD:409353 1/5 (20%)
Ig strand E 195..200 CDD:409353 0/4 (0%)
Ig strand E 195..200 CDD:409353 0/4 (0%)
Ig strand F 209..218 CDD:409353 2/12 (17%)
Ig strand F 209..218 CDD:409353 2/12 (17%)
Ig strand G 221..234 CDD:409353 2/12 (17%)
Ig strand G 221..234 CDD:409353 2/12 (17%)
Ig3_IL1RAP 243..349 CDD:409525 26/105 (25%)
Ig strand B 262..266 CDD:409525 1/3 (33%)
Ig strand C 279..283 CDD:409525 0/3 (0%)
Ig strand E 314..318 CDD:409525 0/3 (0%)
Ig strand F 329..334 CDD:409525 2/4 (50%)
Ig strand G 341..344 CDD:409525 1/2 (50%)
TIR 404..547 CDD:214587 23/118 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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