DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13506 and IGSF5

DIOPT Version :9

Sequence 1:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	XP_011527774.1	Gene:	IGSF5 / 150084	HGNCID:	5952	Length:	497	Species:	Homo sapiens

Alignment Length:	178	Identity:	40/178 - (22%)
Similarity:	70/178 - (39%)	Gaps:	36/178 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 GDDVILNCD-ARNFQLSNAVVWYKNRIII--ANGQNPI-------SQRVQCMLN--NSILLRNVS 136
            |.....||. ::.::|   ::|..:.:::  .....||       |||.....|  :.:::.||.
Human   143 GSQARFNCTVSQGWKL---IMWALSDMVVLSVRPMEPIITNDRFTSQRYDQGGNFTSEMIIHNVE 204

  Fly   137 PEDSDDYYCEILPQRVRQHTALRVGARLSI-LCDDRDITDRSQTFRQGDHHKLECR----TYLPD 196
            |.||.:..|.:      |::.|...|.|:: :..:..|...:....:.:..::.|.    |.|||
Human   205 PSDSGNIRCSL------QNSRLHGSAYLTVQVMGELFIPSVNLVVAENEPCEVTCLPSHWTRLPD 263

  Fly   197 NATIKWSFNDLNGQ------PSSVDNQNGVIILDNVDEKNAGDYQCLA 238
               |.|....|...      |...|.|:.|.||....:.| |...|:|
Human   264 ---ISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSN-GTLTCVA 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653	16/73 (22%)
		IGc2	83..146	CDD:197706	16/73 (22%)
		IG_like	176..254	CDD:214653	18/73 (25%)
		Ig	176..239	CDD:299845	18/73 (25%)
		I-set	258..349	CDD:254352
		Ig	275..348	CDD:143165
IGSF5	XP_011527774.1	IG_like	135..228	CDD:214653	21/93 (23%)
		Ig	<200..230	CDD:299845	10/35 (29%)
		Ig	236..307	CDD:299845	18/74 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930