DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrapper and iglon5

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	356	Identity:	81/356 - (22%)
Similarity:	142/356 - (39%)	Gaps:	80/356 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CSVVR----CLLAALILGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVR 66
            |:::|    .|||.|..|...|:         :.:|..:|..:...|.::|.|.|.::....:..
Zfish     3 CAMLRHALALLLALLWKGPSGAQ---------AAEFGHLPDNITVLEGESVVLRCKIDEEVTHKA 58

  Fly    67 W-HRDDVALVDSRHPELPPPDRIMLWPNG----SLQVANVQSSDTGDYYCEMNSDSGHVVQQHAI 126
            | :|.::....:....|  ..|:.|..|.    |:::..|..:|.|.|.|...:.:    :....
Zfish    59 WLNRSNILFTGTDKWSL--DSRVSLENNNNSDFSIRIERVMVADEGPYTCSFQARN----KPRTA 117

  Fly   127 EVQLAPQVLIEPSDLTEQRI---GAIFEVVCEAQGVPQPVITWR------LN-GNVIQPQSNTGN 181
            .|.|..||.....::::.:.   |....:.|.|.|.|:|.|||:      || |..::
Zfish   118 HVYLIVQVPARIVNISQDKSVNEGEDVNLFCLAVGRPEPTITWKDFKYGLLNEGEFLE------- 175

  Fly   182 RQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPEV----SIPQPVVYTKLGSRAHLE 242
                |.||| |:||...||:.:|||..|....|.:.|.:.|.:    ::|     .::|..|.|.
Zfish   176 ----ITEIK-RHQAEDFECITNNGVAPPDTRKVKVTVNYPPIITDVKNMP-----AQVGKTAILR 230

  Fly   243 CIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYEC 307
            |...|.|.|:.:|:.            .....::::.::.......|.:|:..:|.....|.|.|
Zfish   231 CEAMAVPTASFEWYR------------DDRRPVESDNTLKIKNEKTRSLLLFTNVTEKHFGNYTC 283

  Fly   308 RASNQI-------------SVKSGSVELTGR 325
            .|||::             :|..|:..|.||
Zfish   284 FASNRLGASNASMLLFRPGAVYGGAASLNGR 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	17/87 (20%)
		IG_like	41..118	CDD:214653	17/81 (21%)
		IG_like	145..218	CDD:214653	26/82 (32%)
		Ig	147..219	CDD:299845	26/78 (33%)
		I-set	224..323	CDD:254352	20/115 (17%)
		IGc2	236..314	CDD:197706	17/90 (19%)
		FN3	339..431	CDD:238020
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	19/95 (20%)
		Ig	35..123	CDD:299845	18/93 (19%)
		Ig	125..>183	CDD:299845	18/69 (26%)
		I-set	128..207	CDD:254352	26/90 (29%)
		IG_like	217..298	CDD:214653	18/97 (19%)
		ig	223..296	CDD:278476	17/84 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4772
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.960