Protein Alignment wrapper and OPCML

DIOPT Version :10

• Sequence 1: NP_477404.1
• Gene: wrapper / 37555
• FlyBaseID: FBgn0025878
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_001306032.1
• Gene: OPCML / 4978
• HGNCID: 8143
• Length: 354
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 89/357 - (24%)
• Similarity: 151/357 - (42%)
• Gaps: 61/357 - (17%)

  Fly    40 IPTTV----------KTYENDTVQ------LPCTLNTPFRYVRW-HRDDVALVDSRHPELPPPDR 87
            :||.|          |..:|.||:      |.||::.....|.| :|..:....:....:.|  |
Human    25 VPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDP--R 87

  Fly    88 IMLWPNG----SLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGA 148
            :::..|.    |:.:.||...|.|.|.|.:.:|:.....:..:.||:.||::...||:|... |:
Human    88 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE-GS 151

  Fly   149 IFEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVAN 213
            ...::|.|.|.|:|.:||| :.:|.:.|......:.|.:....|:|:|..||.|.|.|..|.|..
Human   152 SVTLLCLAIGRPEPTVTWR-HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215

  Fly   214 VYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTN 278
            |.:.|.:.|.:|..:. ....:|.:..|.|...|.|.|..:||.....:|.|......|::.:.:
Human   216 VKITVNYPPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMS 279

  Fly   279 RSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQ----- 338
                        .|...:|...|.|.|.|.|:|::...:.|:        .|::|:|.:.
Human   280 ------------TLTFFNVSEKDYGNYTCVATNKLGNTNASI--------TLYEISPSSAVAGPG 324

  Fly   339 ------SSTSHVL--VWQTESLLPIMEFKLKF 362
                  :|.|..|  :|.:.:||  ..|.:||
Human   325 AVIDGVNSASRALACLWLSGTLL--AHFFIKF 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	IG_like	41..118	CDD:214653	24/97 (25%)
		Ig strand B	52..56	CDD:409353	2/9 (22%)
		Ig strand C	64..68	CDD:409353	2/4 (50%)
		Ig strand E	94..98	CDD:409353	1/7 (14%)
		Ig strand F	108..113	CDD:409353	2/4 (50%)
		Ig strand G	122..125	CDD:409353	0/2 (0%)
		Ig	133..219	CDD:472250	27/85 (32%)
		Ig strand B	150..154	CDD:409353	0/3 (0%)
		Ig strand C	163..167	CDD:409353	1/3 (33%)
		Ig strand E	183..187	CDD:409353	1/3 (33%)
		Ig strand F	197..202	CDD:409353	2/4 (50%)
		Ig strand G	211..214	CDD:409353	1/2 (50%)
		Ig_3	222..311	CDD:464046	20/88 (23%)
		FN3	339..431	CDD:238020	9/26 (35%)
OPCML	NP_001306032.1	Ig	44..132	CDD:472250	20/89 (22%)
		Ig strand B	53..57	CDD:409353	1/3 (33%)
		Ig strand C	65..69	CDD:409353	1/3 (33%)
		Ig strand E	98..102	CDD:409353	1/3 (33%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	0/2 (0%)
		Ig_3	135..206	CDD:464046	23/72 (32%)
		Ig	224..312	CDD:472250	22/108 (20%)
		Ig strand B	240..244	CDD:409353	1/3 (33%)
		Ig strand C	253..257	CDD:409353	0/3 (0%)
		Ig strand E	279..283	CDD:409353	1/15 (7%)
		Ig strand F	293..298	CDD:409353	2/4 (50%)
		Ig strand G	306..309	CDD:409353	0/2 (0%)