DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and opcml

DIOPT Version :9

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:NP_001005580.1 Gene:opcml / 449538 ZFINID:ZDB-GENE-040927-3 Length:342 Species:Danio rerio


Alignment Length:322 Identity:76/322 - (23%)
Similarity:137/322 - (42%) Gaps:47/322 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 TVKTYENDTVQLPCTLNTPFRYVRW-HRDDVALVDSRHPELPPPDRIMLWPNG----SLQVANVQ 102
            ||:  :.|:..|.|:::.....|.| :|..:....:....|.|  |::|....    |:::.||.
Zfish    43 TVR--QGDSAVLKCSMDNKVSRVAWLNRTTILFTGNEKWSLDP--RVVLLNTAVNEYSIKILNVN 103

  Fly   103 SSDTGDYYCE-MNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITW 166
            ..|.|.|.|. :.:......:.|.| ||:..:::...:|::... |:...::|.|.|.|:|.|.|
Zfish   104 LYDEGPYVCSILTNKKPESTKVHLI-V
QVPARIVNVSTDVSVNE-GSNVSLMCLAIGRPEPSILW 166

  Fly   167 RLNGNVIQPQSNTGNR---QSLILEIK--SRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSI 226
            :.       :|:.|||   :...:|:.  :::.:|..:|:.||.:..|.|..|.:.|.:.|.:|.
Zfish   167 KF-------RSSKGNRIVTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVTV
NYPPVISR 224

  Fly   227 PQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHM 291
            .:. ..|.:|.:..|.|...|.|.|..:||.....:..|.:....|::            ..:.|
Zfish   225 ARS-TGTAVGQKGVLWCEASAVPLADFQWFKGERRILNGFNGVKIENK------------GKQSM 276

  Fly   292 LVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTSHVLVWQTESLL 353
            |...:|...|.|.|.|.|.|.:.:.:.|:.|.|          ||.....::..:..|.|||
Zfish   277 LTFFNVSEEDYGNYTCVAINTLGITNASIIL
YG----------PGAIHDVNNAALSPTCSLL 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 Ig 41..124 CDD:299845 19/86 (22%)
IG_like 41..118 CDD:214653 19/80 (24%)
IG_like 145..218 CDD:214653 20/77 (26%)
Ig 147..219 CDD:299845 20/76 (26%)
I-set 224..323 CDD:254352 22/98 (22%)
IGc2 236..314 CDD:197706 19/77 (25%)
FN3 339..431 CDD:238020 4/15 (27%)
opcmlNP_001005580.1 Ig 41..129 CDD:299845 21/90 (23%)
IG_like 41..129 CDD:214653 21/90 (23%)
IG_like 139..216 CDD:214653 21/84 (25%)
IGc2 146..202 CDD:197706 15/63 (24%)
I-set 219..307 CDD:254352 23/100 (23%)
ig 223..307 CDD:278476 22/96 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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