DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and dpr17

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	64/279 - (22%)
Similarity:	101/279 - (36%)	Gaps:	67/279 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 NTPFRYVRWHRD--DVALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYY--CEMNSDSGH 119
            |....|:..|||  |.|....|.             |.::.|.|:.:......|  |:::..|..
  Fly   384 NEQHSYLAAHRDGGDGAGSAVRR-------------NLTMPVLNITAQMGNHAYMPCQIHRLSDK 435

  Fly   120 VV------QQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSN 178
            .|      ..|.|.|.       |.:.:.::|..:|::        .....||.|....::|
  Fly   436 PVSWVRMRDNHIISVD-------ETTFIADERFQSIYQ--------EDHDYTWSLQIKYVEP--- 482

  Fly   179 TGNRQSLILEIKSRNQAGLIECVASNGVGEPAV-ANVYLHVLFSPEVSIPQPVVYTKLGSRAHLE 242
                          :.||..||..:.   ||.: |.|:|.::......|.....:.|.||:..|.
  Fly   483 --------------SDAGWYECQMAT---EPKLSAKVHLQIVKPKTELIGDQSRFVKAGSKVALH 530

  Fly   243 CIVEAA--PAATVKWFHHGLPVALGAHSTTHESELQTN--RSVDHYVNAVRHMLVVKSVRNADMG 303
            |||...  |...:.||.....::.....|...::|..|  .:|....|.: ..|::..||..|.|
  Fly   531 CIVRGTLDPPKYIIWFRGQKKISDSDERTGWYTQLDRNIFGTVGDNQNTI-GSLIIPLVRKEDSG 594

  Fly   304 QYECRASNQISVKSGSVEL 322
            .|.|:.||.:||   ||:|
  Fly   595 NYTCQPSNSVSV---SVDL 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	15/74 (20%)
		IG_like	41..118	CDD:214653	13/62 (21%)
		IG_like	145..218	CDD:214653	15/73 (21%)
		Ig	147..219	CDD:299845	14/72 (19%)
		I-set	224..323	CDD:254352	30/103 (29%)
		IGc2	236..314	CDD:197706	23/81 (28%)
		FN3	339..431	CDD:238020
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	18/108 (17%)
		Ig	415..507	CDD:299845	23/126 (18%)
		IG_like	521..612	CDD:214653	29/94 (31%)
		IGc2	524..605	CDD:197706	23/81 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900