DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and CG7166

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	111/409 - (27%)
Similarity:	194/409 - (47%)	Gaps:	23/409 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRWHRDDVALVDSRHPELPPPDRIMLWP 92
            |:....:.||.|.....|....:|::|||.:.....:|...|...:::.:.|.::....|..:..
  Fly    32 NDPPTTAPKFLSRGHLYKVIVGETIELPCKVQNLGSFVLLWRKGSSVLTAGHLKITRDQRFKIVG 96

  Fly    93 NGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEP-SDLTEQRIGAIFEVVCEA 156
            :.:||:..|::.|.|||.|:: .|..:..|.|.:|:.:.|.:...| :.....|.|:...:.|:|
  Fly    97 DYNLQINGVKTQDAGDYICQL-GDQENRDQVHTVEILVPPTLRALPHNGQVTARKGSTVTLECKA 160

  Fly   157 QGVPQPVITWRLNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFS 221
            .|.|.|.|.| ...:|....::..:..:||||...|:.||..:|.|.|||.:....::.|.:|..
  Fly   161 SGNPVPTIFW-FKKDVFSGPTHLSDSSTLILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSP 224

  Fly   222 PEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVN 286
            ||:::.:..|:...|....|.|||.....:.:.|:.:...:           :....||:  |..
  Fly   225 PEITVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQNSFLL-----------DATDRRSM--YPR 276

  Fly   287 AVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTSHV-LVWQTE 350
            ..|:.|::::.:..|.|.|.|.|.|.:......:|::|||.|..| |:|.......|. |.|..|
  Fly   277 DDRYSLIIRNFQPTDFGNYSCVADNALGRTKKYIEVSGRPGPADF-ISPALSGFLDHYNLTWTIE 340

  Fly   351 SLLPIMEFKLKFRQIPSNNVTRQVRTNWTELTI---PAQATNGLIYITTYTLHGLQPASLYEVSV 412
            |:.|:.|.||.:|::..|. |.|....|.|..|   |.: |:|..::.:|.:..|:..::||..|
  Fly   341 SIPPLDEIKLLYRRLLMNE-TYQHPGKWHEYHIKPTPIR-TDGSHFLMSYLVKNLEHNAVYEAIV 403

  Fly   413 LARNSFGWSDNSKIVRFAT 431
            .|:|.:||::.|.|.:|.|
  Fly   404 QAKNKYGWNEISDIHQFYT 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	19/82 (23%)
		IG_like	41..118	CDD:214653	18/76 (24%)
		IG_like	145..218	CDD:214653	23/72 (32%)
		Ig	147..219	CDD:299845	22/71 (31%)
		I-set	224..323	CDD:254352	19/98 (19%)
		IGc2	236..314	CDD:197706	17/77 (22%)
		FN3	339..431	CDD:238020	31/95 (33%)
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	20/83 (24%)
		Ig	56..116	CDD:143165	14/59 (24%)
		IG_like	144..221	CDD:214653	23/77 (30%)
		IGc2	151..209	CDD:197706	19/58 (33%)
		IG_like	232..313	CDD:214653	19/93 (20%)
		Ig	242..311	CDD:143165	16/81 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4772
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D332048at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14108
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45080
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.970