DRSC/TRiP Functional Genomics Resources

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Protein Alignment wrapper and Fgfrl1

DIOPT Version :9

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:NP_954545.1 Gene:Fgfrl1 / 360903 RGDID:735156 Length:529 Species:Rattus norvegicus


Alignment Length:383 Identity:78/383 - (20%)
Similarity:129/383 - (33%) Gaps:92/383 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 TVQLPCTL-NTPFRYVRWHRDDVALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYYCEMN 114
            ||:|.|.: ..|.....|.:|...:....       .|..:.|.| |:|..|::.|.|.|.|:..
  Rat    42 TVRLQCPVEGDPPPLTMWTKDGRTIHSGW-------SRFRVLPQG-LKVKEVEAEDAGVYVCKAT 98

  Fly   115 SDSGHVV--------------------------QQHAIEVQLAPQVLIEPSDLTE----QRIGAI 149
            :..|.:.                          |:..:..|.|.....:||.:..    :.:|:.
  Rat    99 NGFGSLSVNYTLII
MDDISPGKENPGPGGSSGGQEDPVSQQWARPRFTQPSKMRRRVIARPVGSS 163

  Fly   150 FEVVCEAQGVPQPVITWRLNGNV---IQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAV 211
            ..:.|.|.|.|:|.|.|..:...   ::...:...:.:|.|:......:|...|..||..|  |:
  Rat   164 VRLKCVASGHPRPDIMWMKDDQTLTRLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNRAG--AI 226

  Fly   212 -----ANVYLHVLFSPEVSIPQPVVYT-KLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTT 270
                 .:|.......|.::...||..| ..|.....:|.|.:.....::|.......:.|.|::|
  Rat   227 NATYKVDV
IQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNST 291

  Fly   271 HESELQT----------NRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQI--SVKSG----- 318
            .:...|.          :|....|:|    .|::...|..|.|.|.|..:|.:  |.:|.     
  Rat   292 IDVGGQKFVVLPTGDVWSRPDGSYLN----KLLISRARQDDAGMYICLGANTMGYSFRSAFLTVL 352

  Fly   319 ------------SVELTGRPMPCLFKINPGTQSSTSHVLVW--QTE-------SLLPI 355
                        |...|..|.|.:..|..|.......||:|  ||:       |.||:
  Rat   353 PDPKPPGPPVAHSSSTTSLPWPVVIGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPV 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 Ig 41..124 CDD:299845 19/99 (19%)
IG_like 41..118 CDD:214653 17/67 (25%)
IG_like 145..218 CDD:214653 17/80 (21%)
Ig 147..219 CDD:299845 17/79 (22%)
I-set 224..323 CDD:254352 24/128 (19%)
IGc2 236..314 CDD:197706 18/89 (20%)
FN3 339..431 CDD:238020 8/26 (31%)
Fgfrl1NP_954545.1 I-set 29..112 CDD:400151 18/77 (23%)
Ig strand A' 35..38 CDD:409353
Ig strand B 41..50 CDD:409353 4/7 (57%)
Ig strand C 56..61 CDD:409353 1/4 (25%)
Ig strand C' 64..67 CDD:409353 0/2 (0%)
Ig strand D 72..77 CDD:409353 1/4 (25%)
Ig strand E 78..84 CDD:409353 3/6 (50%)
Ig strand F 91..99 CDD:409353 3/7 (43%)
Ig strand G 102..112 CDD:409353 1/9 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 117..152 5/34 (15%)
IgI_2_FGFRL1-like 143..234 CDD:409442 18/92 (20%)
Ig strand B 164..168 CDD:409442 0/3 (0%)
Ig strand C 177..181 CDD:409442 1/3 (33%)
Ig strand E 200..204 CDD:409442 1/3 (33%)
Ig strand F 214..219 CDD:409442 1/4 (25%)
Ig strand G 227..230 CDD:409442 0/2 (0%)
Ig 242..350 CDD:416386 24/111 (22%)
Ig strand A 242..245 CDD:409353 1/2 (50%)
Ig strand A' 249..253 CDD:409353 2/3 (67%)
Ig strand B 261..268 CDD:409353 2/6 (33%)
Ig strand C 272..279 CDD:409353 1/6 (17%)
Ig strand D 304..309 CDD:409353 0/4 (0%)
Ig strand E 317..322 CDD:409353 2/8 (25%)
Ig strand F 330..338 CDD:409353 3/7 (43%)
Ig strand G 341..349 CDD:409353 2/7 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 405..427 3/6 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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