DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and DIP-zeta

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_723441.2	Gene:	DIP-zeta / 34231	FlyBaseID:	FBgn0051708	Length:	532	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	93/354 - (26%)
Similarity:	145/354 - (40%)	Gaps:	53/354 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRY-VRW-HRDDVAL------ 74
            |..|..|.:|...:||        .||....|  |:|.|::.....| |.| |.:..|:
  Fly   106 LNIVVEEPEFTEYIEN--------VTVPAGRN--VKLGCSVKNLGSYKVAWMHFEQSAILTVHNH 160

  Fly    75 VDSRHPEL----PPPDRIMLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQV- 134
            |.:|:|.:    ...||...|   .|.:.||...|.|.|.|::|:.:.. .|...:.|.:.|.:
  Fly   161 VITRNPRISVTHDKHDRHRTW---YLHINNVHEEDRGRYMCQINTVTAK-TQFGYLNVVVPPNID 221

  Fly   135 -LIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGN---VIQPQSNTGNRQSLILEIK--SRN 193
             .:..||:. .|.||...:.|.|.|.|:|:|.|:.:.|   .|.........:...|||.  ||.
  Fly   222 DSLSSSDVI-VREGANISLRCRASGSPRPIIKWKRDDNSRIAINKNHIVNEWEGDTLEITRISRL 285

  Fly   194 QAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHH 258
            ..|...|:|||||.......:.:.|.|.|.:.||..:|....|....:||..||.|.:...|...
  Fly   286 DMGAYLCIASNGVPPTVSKRIKVSVDFPPMLLIPHQLVGAPEGFNVTIECFTEAHPTSLNYWTRG 350

  Fly   259 GLPVALGAHSTTHESELQTNRSVDHYVNAVRHM-LVVKSVRNADMGQYECRASNQISVKSGSVEL 322
            ..|:   .|. :|:.:::....:..|..   || |.:.:|.:.|.|.|:|.|.|......|.:.
  Fly   351 EGPI---IHD-SHKYKVEATVGLPAYKT---HMKLTIINVSSGDDGIYKCVAKNPRGETDGIIR- 407

  Fly   323 TGRPMPCLFKINPGTQSSTSHVLVWQTES 351
                   |:...|.|.:|:.   ::.|::
  Fly   408 -------LYVSYPPTTASSG---IYSTDT 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	26/94 (28%)
		IG_like	41..118	CDD:214653	25/88 (28%)
		IG_like	145..218	CDD:214653	24/77 (31%)
		Ig	147..219	CDD:299845	23/76 (30%)
		I-set	224..323	CDD:254352	25/99 (25%)
		IGc2	236..314	CDD:197706	21/78 (27%)
		FN3	339..431	CDD:238020	2/13 (15%)
DIP-zeta	NP_723441.2	IG_like	120..216	CDD:214653	29/109 (27%)
		Ig	130..200	CDD:143165	21/72 (29%)
		I-set	226..310	CDD:254352	26/84 (31%)
		IGc2	233..298	CDD:197706	21/64 (33%)
		Ig	313..410	CDD:299845	27/111 (24%)
		IG_like	325..410	CDD:214653	23/99 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810