DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrapper and DIP-eta

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001188701.2	Gene:	DIP-eta / 33793	FlyBaseID:	FBgn0031725	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	89/390 - (22%)
Similarity:	152/390 - (38%)	Gaps:	85/390 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CSVVRCLLAALILGQVQAELDFNNDLE------NSQKFKSIPTTVKTYENDTVQLPCTLNT--PF 62
            |....|.|:.::|..:.::..:...:|      ...||.|....:.........|.|.:..  |:
  Fly     8 CRKQTCALSVILLLILMSQQCYPQRVEVPAEVIVDPKFSSPIVNMTAPVGRDAFLTCVVQDLGPY 72

  Fly    63 RYVRWHRDD-----------------VALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYY 110
            : |.|.|.|                 :.:.:|.|         ..|   ::::.:::.||.|.|.
  Fly    73 K-VAWLRVDTQTILTIQNHVITKNQRIGIANSEH---------KTW---TMRIKDIKESDKGWYM 124

  Fly   111 CEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQ--RIGAIFEVVCEAQGVPQPVITWRLNGNVI 173
            |::|:|. ...|...::|.:.|.:|..|:. |:.  |.|:...:.|.|.|.|:|.||||....|
  Fly   125 CQINTDP-MKSQMGYLDVVVPPDILDYPTS-TDMVVREGSNVTLKCAATGSPEPTITWRRESGV- 186

  Fly   174 QP-QSNTGNR------QSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVV 231
             | :..||..      ..|::....|:..|...|:|||||.......:.|.|.|.|.:::...::
  Fly   187 -PIELATGEEVMSIEGTDLVIPNVRRHHMGAYLCIASNGVPPSVSKRITLVVHFPPMITVQNQLI 250

  Fly   232 YTKLGSRAHLECIVEAAPAATVKWF-HHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVK 295
            ....|....|:|..||.|.:...|. ..|..|..|...:.:.:|      :..|.|::|  |.:.
  Fly   251 GAVEGKGVTLDCESEAYPKSINYWTRERGEIVPPGGKYSANVTE------IGGYRNSMR--LHIN 307

  Fly   296 SVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPG-----------------TQSSTSH 343
            .:..|:.|.|.|.|.|.:....|:::        |::|.|.                 |:||.||
  Fly   308 PLTQAEFGSYRCVAKNSLGDTDGTIK--------LYRIPPNAVNYVENFEARHKGKKRTKSSESH 364

Fly 344 343
Fly 365 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	18/101 (18%)
		IG_like	41..118	CDD:214653	17/95 (18%)
		IG_like	145..218	CDD:214653	25/79 (32%)
		Ig	147..219	CDD:299845	24/78 (31%)
		I-set	224..323	CDD:254352	22/99 (22%)
		IGc2	236..314	CDD:197706	21/78 (27%)
		FN3	339..431	CDD:238020	4/5 (80%)
DIP-eta	NP_001188701.2	Ig	51..141	CDD:299845	18/103 (17%)
		IG_like	51..137	CDD:214653	18/99 (18%)
		IG_like	153..237	CDD:214653	26/86 (30%)
		Ig	161..224	CDD:299845	20/64 (31%)
		IG_like	252..335	CDD:214653	22/98 (22%)
		Ig	258..333	CDD:143165	21/82 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810