DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and CG6867

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_573262.2	Gene:	CG6867 / 32782	FlyBaseID:	FBgn0030887	Length:	949	Species:	Drosophila melanogaster

Alignment Length:	455	Identity:	96/455 - (21%)
Similarity:	164/455 - (36%)	Gaps:	139/455 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 RDDVALVDSRHPELPPPDR-------------------------IMLW----PNGSLQVANVQSS 104
            :|.:::...:..:.||.:|                         |..|    ||||      .|:
  Fly   367 KDGLSITGPKGAQGPPGERGLKGIAGPRGRPGKPGTNGIPGVPGINAWKLQYPNGS------SSN 425

  Fly   105 DTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRI-----------GAIFEVVCEAQG 158
            |                            :||.|| :|:.::           |....:.|.|.|
  Fly   426 D----------------------------LLIPPS-ITDIQVPDFQRTVIVEEGRSLNLSCTATG 461

  Fly   159 VPQPVITWR------LNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLH 217
            .|.|.:.||      :|.|.::..|.:|  |.|.....:|:|.....|.|:||:...|.|...:.
  Fly   462 TPTPQVEWRREDGRTINVNGVEMASISG--QFLRFTNITRHQMAAYTCFANNGIAPVANATYLVE 524

  Fly   218 VLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESEL---QTNR 279
            |.|:|.:|:.:.::|.:..|.|.|||:|||.|.|...|            ...::.::   ....
  Fly   525 VQFAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYW------------ERAYDGKILDPSDKY 577

  Fly   280 SVDHYVNAVR--HMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMPCLFKINPGTQSSTS 342
            .::.|....:  ..|.:.::|..|.|.|.|.|.|:::....:.|:..:..      |..|....:
  Fly   578 GIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDP------NSETPYVGN 636

  Fly   343 HVLVW---QTESLLPIMEFKLKFRQIPSNNVTR---QVRTNWTELTIPAQATNGLIYITTYTLHG 401
            ::.|:   ..||..|:.:      |.|..::.:   .:..|:     ..|||..|.|      .|
  Fly   637 NMKVYGQRPPESECPVCD------QCPDPSLYQCKDSILNNF-----EIQATGNLSY------PG 684

  Fly   402 L--QPASLYEVSVLARNSFGWSDNSKIVRFATGGEVELPNYSTESELQDDFTEEDFHN--EITQR 462
            |  :|.:.|..:|      |.....|:|....|..:..|:..::.|......|.|.:|  |.|.|
  Fly   685 LPKRPKTCYLYAV------GKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTTR 743

Fly 463 462
Fly 744 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	12/83 (14%)
		IG_like	41..118	CDD:214653	12/77 (16%)
		IG_like	145..218	CDD:214653	22/89 (25%)
		Ig	147..219	CDD:299845	22/77 (29%)
		I-set	224..323	CDD:254352	23/103 (22%)
		IGc2	236..314	CDD:197706	20/82 (24%)
		FN3	339..431	CDD:238020	20/99 (20%)
CG6867	NP_573262.2	Collagen	306..364	CDD:189968
		IG_like	442..525	CDD:214653	22/84 (26%)
		IGc2	449..511	CDD:197706	18/63 (29%)
		IG_like	544..612	CDD:214653	19/79 (24%)
		Ig	546..612	CDD:143165	18/77 (23%)
		OLF	694..937	CDD:280371	13/56 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910