DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and dpr18

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	79/414 - (19%)
Similarity:	129/414 - (31%)	Gaps:	150/414 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SVVRCLLAALILG-QVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRWHRD 70
            |::|.|..||::| |||.               ...|:|:|                      :.
  Fly    31 SLLRLLTIALVIGSQVQV---------------LYTTSVET----------------------KS 58

  Fly    71 DVALVDSRHPELPPPDRIMLWPN-----GSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQL 130
            ..|...||:.|    :|.:|:.:     .:|..|:..|:.....|...:.|......|..||...
  Fly    59 PSASEQSRNGE----NRSLLFDDYNKTKSTLSTADYLSATRATLYAFSSQDQDEDHSQMPIEASN 119

  Fly   131 APQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNRQ--SLILEIKSRN 193
            ||.                           .|:.|....|.:  |....|:.:  |..|.||:..
  Fly   120 APH---------------------------SPIPTKMSRGKI--PMETPGSMEFSSNSLPIKNVG 155

  Fly   194 QAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECI----VEAAPAATVK 254
            ....:..|..     |..|...|.|   ...::.||:..|:  :|.|....    |...|.:...
  Fly   156 TTDQLTTVTM-----PTTAFASLKV---DRSTMKQPIDSTR--TRNHWTASGFARVTERPRSKHH 210

  Fly   255 WFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMG-------QYECRASNQ 312
            ..||..|.        .|..:.:..|.|:.|:||.  |..::|.|..:|       .:..|.:.:
  Fly   211 HEHHWGPF--------FEEPINSATSGDNLVSAVH--LFTEAVLNCRVGMLKDKTVMWVRRTAEK 265

  Fly   313 ISVKS-GSVELTGRPMPCLFKINPGTQSSTSHVLVWQTESLLPIMEFKLKFRQIPSNNVTRQVRT 376
            :|:.: |:|..:|.|                              ..::|| |.|:
  Fly   266 VSLLTVGNVTYSGDP------------------------------RIRVKF-QYPN--------- 290

  Fly   377 NWTELTIPAQATNGLIYITTYTLH 400
            ||..|..|.|..:..:|:...:.|
  Fly   291 NWRLLINPTQTEDAGVYMCQVSTH 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	14/87 (16%)
		IG_like	41..118	CDD:214653	14/81 (17%)
		IG_like	145..218	CDD:214653	13/74 (18%)
		Ig	147..219	CDD:299845	13/73 (18%)
		I-set	224..323	CDD:254352	24/110 (22%)
		IGc2	236..314	CDD:197706	18/88 (20%)
		FN3	339..431	CDD:238020	11/62 (18%)
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	20/113 (18%)
		Ig	<258..326	CDD:299845	17/97 (18%)
		IGc2	<417..461	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900