DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and Negr1

DIOPT Version :9

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:232 Identity:64/232 - (27%)
Similarity:99/232 - (42%) Gaps:25/232 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 SLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGV 159
            |||:.||..:|.|.|.|.:.:.......|..:.||:.|::....:|:|... |....:.|.|.|.
Mouse    96 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV
QVPPKIYDISNDMTINE-GTNVTLTCLATGK 159

  Fly   160 PQPVITWRLNGNVIQPQSNT-GNRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPE 223
            |:|||:||    .|.|.:.. .|.|.|.:...:|:|||..||.|.|.|..|.|..|.:.|.|:|.
Mouse   160 PEPVISWR----HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPT 220

  Fly   224 VSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESEL---QTNRSVDHYV 285
            :...:....|. |....:.|.....|....:|:             ..|..|   |....:.:: 
Mouse   221 IQEIKSGTVTP-GRSGLIRCEGAGVPPPAFEWY-------------KGEKRLFNGQQGIIIQNF- 270

  Fly   286 NAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVEL 322
             :.|.:|.|.:|.....|.|.|.|:|::...:.|:.|
Mouse   271 -STRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 Ig 41..124 CDD:299845 9/28 (32%)
IG_like 41..118 CDD:214653 9/22 (41%)
IG_like 145..218 CDD:214653 27/73 (37%)
Ig 147..219 CDD:299845 27/72 (38%)
I-set 224..323 CDD:254352 19/102 (19%)
IGc2 236..314 CDD:197706 16/80 (20%)
FN3 339..431 CDD:238020
Negr1XP_036019026.1 FR1 38..55 CDD:409353
Ig strand A' 40..46 CDD:409353
IG_like 41..129 CDD:214653 10/32 (31%)
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353 9/18 (50%)
Ig strand D 84..91 CDD:409353
Ig strand E 94..100 CDD:409353 3/3 (100%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 0/3 (0%)
Ig strand G 120..129 CDD:409353 1/8 (13%)
FR4 122..129 CDD:409353 1/6 (17%)
Ig strand A' 139..144 CDD:409353 1/4 (25%)
IGc2 146..204 CDD:197706 23/62 (37%)
Ig strand B 150..157 CDD:409353 1/6 (17%)
Ig strand C 163..168 CDD:409353 4/8 (50%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 2/5 (40%)
Ig strand F 193..200 CDD:409353 3/6 (50%)
Ig_3 219..295 CDD:404760 17/91 (19%)
putative Ig strand A 219..225 CDD:409353 1/5 (20%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 2/4 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.